Machine Learning Research Lead, Alzheimer's Disease Initiative

Arc Institute
Arc Institute logo
Location
Palo Alto, CA
Job Type
Full-time
Reposted
July 4, 2026
Originally posted Feb 15, 2026
Views
19
Salary Range
$339k - $401k USD

Job Description

Arc Institute seeks a scientific leader to establish a new ML team within its Computational Technology Center. The role focuses on developing sophisticated machine learning foundation models to capture cell states and infer gene regulatory networks for Alzheimer's disease research.

Responsibilities include building a research team, developing interpretable ML approaches, collaborating with experimentalists on cellular models, and publishing high-impact research.

Key Requirements

  • PhD in Computational Biology, Bioinformatics, Machine Learning, or related field
  • 7+ years relevant experience with minimum 3 years people management
  • Expertise in ML applications to biological datasets, particularly single-cell profiling and foundation models
  • Strong background in interpretable ML methods (variational inference, causal modeling)
  • Advanced PyTorch skills and large-scale model training experience
  • Publications in top-tier computational biology/ML journals
  • Proven technical leadership ability
  • Neurodegeneration/Alzheimer's research background preferred

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Frequently Asked Questions

Where is the job located, and is it remote, hybrid, or on-site?
The position is located in Palo Alto, CA. The provided text does not specify a remote or hybrid work-mode policy.
What are the key responsibilities of this role?
You will build and lead a new machine learning research team, develop interpretable ML foundation models to capture cell states and infer gene regulatory networks, collaborate with experimentalists on cellular models, and publish high-impact research.
What qualifications and experience are required?
You need a PhD in Computational Biology, Bioinformatics, ML, or a related field, and 7+ years of relevant experience, including at least 3 years of people management. Requirements include expertise in biological ML applications, interpretable ML methods, advanced PyTorch skills, large-scale model training, and top-tier publications. A background in neurodegeneration or Alzheimer's is preferred.
Who will I be working with and leading?
You will be establishing and leading a new machine learning research team within Arc Institute's Computational Technology Center, and collaborating closely with experimentalists on cellular models.

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Job Information

Source: manual
AI Relevance: 95/100 (Highly relevant)
Remote Type: onsite
Experience: lead
Skills & Tags:
machine-learning foundation-models single-cell alzheimers pytorch leadership computational-biology

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