Director, Head of Computational Design

GSK
Location
Cambridge, MA; Collegeville, PA; Rixensart, Belgium; Siena, Italy
Job Type
Full-time
Posted
February 19, 2026
Views
10
Salary Range
$178k - $297k USD

Job Description

This leadership role oversees the design and application of new advanced computational methods, including Large Language Models (LLMs) and AI, for cutting-edge mRNA design and next-generation vaccine development.

The position guides optimization of nucleic acid therapeutics, vaccine platforms, and delivery systems using in silico solutions combined with active learning workflows.

Key Responsibilities

  • Lead a multidisciplinary computational design team
  • Direct advanced computational methodologies including structural bioinformatics and molecular modeling
  • Drive AI/LLM applications for de novo design and predictive modeling
  • Embed computational experts within discovery project teams
  • Establish active learning loops connecting predictions with experimental validation
  • Collaborate with leadership across discovery, translational, and clinical stages

Basic Qualifications

  • PhD in Computational Biology, Data Science, Mathematics, Physics, Engineering, or Bioinformatics
  • 8+ years scientific experience
  • 4+ years direct/matrix people management with international leadership
  • Strong theoretical background in quantitative sciences applied to biology
  • Publication record in relevant expertise areas

Preferred Qualifications

  • Advanced molecular modeling and simulation expertise
  • Structural bioinformatics and protein engineering background
  • AI/LLM application experience for mRNA design
  • Nucleic acid therapeutics computational design background
  • Active learning framework experience

Get Similar Jobs in Your Inbox

Weekly digest of top bioinformatics jobs. No spam.

Ready to Apply?

Apply for this Position

You'll be redirected to the company's application page

Share this job:

Job Information

Source: manual
AI Relevance: 94/100 (Highly relevant)
Remote Type: onsite
Experience: director
Allowed Locations: Cambridge, MA; Collegeville, PA; Rixensart, Belgium; Siena, Italy
Skills & Tags:
computational biology AI LLM mRNA bioinformatics leadership