Senior/Staff Applied Scientist, Multimodal Representation Learning (Oncology)

Pathos
Pathos logo
Location
New York City, NY
Job Type
Full-time
Reposted
June 11, 2026
Originally posted Mar 31, 2026
Views
104
Salary Range
$150k - $200k USD

Job Description

Pathos seeks a specialized scientist to develop their Oncology Foundation Model (OFM) stack. The role focuses on designing multimodal AI systems that integrate clinical text, genomics, imaging, and molecular data to improve drug development decisions.

Key Responsibilities

  • Design and implement multimodal pretraining strategies for oncology data
  • Build cross-modality alignment between clinical narratives and molecular signals
  • Create evaluation frameworks beyond standard metrics (ablations, cohort-shift testing, temporal generalization)
  • Partner with engineering on scalable GPU training infrastructure
  • Package outputs for internal science teams with uncertainty estimates and interpretability

Required Qualifications

  • PhD in ML/AI, CS, Statistics, Computational Biology, or related field
  • Deep PyTorch experience with large model training
  • Demonstrated ability to design and rigorously evaluate representation learning approaches
  • Comfort with ambiguous problems and iterative execution

Strongly Preferred

  • Multimodal foundation model experience
  • Domain expertise in clinical EHR, molecular/omics modeling, or pathology imaging
  • Understanding of censoring, batch effects, and confounding in biomedical data

Nice to Have

  • Distributed training experience (FSDP/DeepSpeed)
  • Alignment methods and robustness evaluation
  • Publications at NeurIPS/ICML/ICLR/MLHC or impactful open-source work

Frequently Asked Questions

Where is the job located, and is it remote, hybrid, or on-site?
The job is located in New York City, NY. The posting does not specify a remote or hybrid work-mode policy, indicating it is based at the New York City location.
What are the key responsibilities of this role?
You will design multimodal pretraining strategies and cross-modality alignment for oncology data, build rigorous evaluation frameworks, partner with engineering on scalable GPU training infrastructure, and package outputs with uncertainty estimates and interpretability for internal science teams.
What qualifications and experience are required?
You must have a PhD in ML/AI, CS, Statistics, Computational Biology, or a related field. Additionally, you need deep PyTorch experience with large model training, a demonstrated ability to design and evaluate representation learning approaches, and comfort with ambiguity.
Are there any preferred or 'nice to have' skills for this position?
Preferred skills include multimodal foundation model experience, biomedical domain expertise, and understanding confounding data. Nice-to-have skills include distributed training (FSDP/DeepSpeed), alignment methods, robustness evaluation, and publications at top ML conferences or impactful open-source work.

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Job Information

Source: manual
AI Relevance: 95/100 (Highly relevant)
Remote Type: hybrid
Experience: Senior
Allowed Locations: Worldwide
Skills & Tags:
machine learning foundation models multimodal oncology PyTorch deep learning representation learning AI

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