Senior Scientist II, Computational Biology

Senior Scientist II, Computational Biology position at AbbVie in Worcester, MA, focusing on integrating statistical and computational methods into multimodal data workflows.

Key Responsibilities

• Integrate statistical and computational methods into multimodal data workflows (imaging, spatial omics)
• Develop scalable pipelines for hypothesis testing, causal inference, and predictive modeling
• Lead experimental design and statistical planning, including power calculations and randomization
• Collaborate with discovery scientists, translational researchers, and bioinformaticians
• Ensure statistical rigor supporting go/no-go decisions and milestone reviews
• Mentor junior scientists and foster collaborative research environments

Requirements

• Degree in Biophysics, Biology, Mathematics, Engineering, Pharmacology or related field
• 12+ years (BS), 10+ years (MS), or 4+ years (PhD) experience in computational biology and life science research
• Minimum 3 years of hands-on computational analysis and statistics work
• Strong biological domain knowledge bridging computational and experimental perspectives
• Exceptional written and verbal communication skills

Preferred

• Experience with imaging technologies and functional assays for complex in vitro models
• Proven record of developing or deploying statistical or AI/ML tools
• Experience with 3D tissue models and organoid research

Work Arrangement: On-site position requiring Tuesday-Thursday office presence; ~5% travel.