Scientist, Reproductive & Molecular Biology

Company Summary

We are building a new venture, FL122, pioneering genomic technologies at the intersection of human health and assisted reproduction. The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Tessera Therapeutics, and Quotient Therapeutics. We are an equal opportunity employer.

Position Summary

We are seeking a Scientist with experience at the intersection of reproductive biology and molecular biology to help build the experimental foundation of the company’s scientific platform. As an early scientific team member, you will contribute to the development of core laboratory workflows spanning human gamete handling and molecular characterization, support the establishment of technical standards, and help execute the experimental strategy in close collaboration with senior scientists and leadership.

We are looking for someone who is highly hands-on, adaptable, and excited to operate across disciplines. The ideal candidate brings a strong foundation from IVF or embryology laboratory environments, combined with experience in molecular biology techniques and a willingness to learn and implement new methods. This role requires attention to detail, comfort working with sensitive human samples, and a collaborative mindset suited for a fast-paced startup environment.

Key Responsibilities

Perform and support IVF laboratory procedures, including preparation and handling of human gametes in a BSL2 environment with strict adherence to quality and reproducibility standards

Execute workflows related to ART techniques such as intra-cytoplasmic sperm injection (ICSI) and related embryology methods, contributing to protocol optimization and standardization

Conduct molecular biology experiments, including nucleic acid extraction, amplification, and QC from low-input or sensitive samples

Contribute to the development and optimization of workflows for integrating embryology procedures with downstream molecular analyses

Support implementation of instrumentation, reagents, and workflows to enable robust and scalable experimental operations

Assist in transcriptomic workflows (e.g., RNA-seq), including sample preparation, library preparation, and coordination with sequencing efforts

Analyze and communicate experimental results clearly, troubleshoot challenges, and iterate on protocols

Collaborate across internal teams and incorporate feedback from external advisors into experimental plans

Requirements

Prior hands-on experience in IVF or embryology laboratory settings, including handling human gametes and performing procedures such as ICSI or related workflows

Ph.D. in biology, molecular biology, genetics, reproductive biology, or a related discipline strongly preferred; exceptional candidates with a Master’s degree/ relevant hands-on experience will also be considered

Strong foundation in molecular biology techniques, with demonstrated ability to learn and adapt to new experimental methods