Sr. Bioinformatics Scientist – cfDNA Technology Development
Personalis
Location
Fremont, CA
Job Type
Full-time
Posted
May 8, 2026
Views
105
Salary Range
$155k - $190k
USD
Job Description
Personalis develops advanced genomics solutions for precision oncology. This role focuses on developing the NeXT Personal platform — an ultra-sensitive, tumor-informed, WGS-based liquid biopsy assay for detecting minimal residual disease and cancer recurrence.
Key Responsibilities
- Design and develop cell-free DNA platforms, particularly the NeXT Personal MRD liquid biopsy system
- Conduct cross-functional scientific projects evaluating product feasibility and clinical advantages
- Analyze large genomics datasets using novel methodologies
- Translate research findings into production-ready products
- Publish findings and present at industry conferences
Required Qualifications
- PhD in bioinformatics, genomics, or related discipline
- Extensive cancer genomics experience
- Proficiency with somatic mutation detection and filtering
- Hands-on cancer liquid biopsy analysis experience
- Programming competency in Python, R, or similar languages
- Demonstrated ability designing experimental approaches for complex projects
- Track record publishing and presenting scientific results
Salary: $155,000 - $190,000. Hybrid (Mon/Tue onsite).
Frequently Asked Questions
Where is this job located, and is it remote, hybrid, or on-site?
This position is located in Fremont, CA, and follows a hybrid work model requiring on-site work on Mondays and Tuesdays.
What is the salary range for this position?
The salary range for this role is $155,000 to $190,000.
What are the key responsibilities of this role?
You will design and develop cell-free DNA platforms, analyze large genomics datasets, translate research into production-ready products, and present findings at conferences.
What qualifications are required for this role?
A PhD in bioinformatics, genomics, or a related discipline, extensive cancer genomics experience, and programming competency in Python or R are required.
What will I be working on in this role?
You will be developing the NeXT Personal platform, an ultra-sensitive liquid biopsy assay for detecting minimal residual disease and cancer recurrence.
Job Information
Source:
manual
AI Relevance:
95/100
(Highly relevant)
Remote Type:
hybrid
Experience:
Senior
Allowed Locations:
Worldwide
Skills & Tags:
bioinformatics
cfDNA
liquid biopsy
cancer genomics
MRD
WGS
precision oncology
Python
R
somatic mutations
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