Principal Statistical Programmer
Alnylam Pharmaceuticals
Location
United States
Job Type
Full-time
Posted
May 8, 2026
Views
108
Salary Range
$151k - $205k
USD
Job Description
Alnylam Pharmaceuticals seeks a Principal Statistical Programmer to provide expert-level hands-on programming support and technical leadership to develop, maintain, validate, and run SAS programs that access, visualize, analyze, and report clinical trial data.
Key Responsibilities
- Write programs that produce or validate tables, listings, figures and analysis datasets for clinical studies or complex integrated analyses for submission
- Develop and follow good programming practices, including documenting SAS and R code
- Plan and coordinate project work to ensure timely, quality delivery across multiple projects
- Create and validate global macros or systems that streamline repetitive operations
- Provide input into or lead general standardization efforts (CRFs, query checks, standard programs)
- Review DMP, eCRF specs, statistical analysis plans, and related documents
- Partner with or oversee CROs or programming vendors
Required Qualifications
- 8+ years pharmaceutical/biotech/CRO SAS programming experience
- Knowledge of clinical trials and experience reporting results for submission
- Experience constructing technical programming specifications and producing complex validated programs
- Strong experience with CDISC standards (SDTM, ADaM, Define xml)
- Excellent knowledge of SAS Macro, SAS/SQL, SAS/GRAPH, and SAS/STAT
- Bachelor's degree required, Master's preferred
- R programming experience preferred
Salary: $151,300 - $204,700
Frequently Asked Questions
Where is this job located?
This position is located in the United States.
What qualifications are required for this role?
You need 8+ years of pharmaceutical/biotech/CRO SAS programming experience and strong knowledge of CDISC standards. A Bachelor's degree is required; a Master's is preferred. R programming experience is also preferred.
What are the main responsibilities of the Principal Statistical Programmer?
You'll write programs to produce and validate tables, listings, figures, and analysis datasets for clinical studies, plus plan and coordinate project work. Developing good programming practices and reviewing study documents are also key.
What is the salary range for this position?
The salary range is $151,300 - $204,700.
What programming skills are needed?
Excellent knowledge of SAS Macro, SAS/SQL, SAS/GRAPH, and SAS/STAT is required. R programming experience is preferred.
Job Information
Source:
manual
AI Relevance:
80/100
(Highly relevant)
Remote Type:
hybrid
Experience:
Senior
Allowed Locations:
Worldwide
Skills & Tags:
statistical programming
SAS
R
CDISC
SDTM
ADaM
clinical trials
regulatory submissions
RNAi
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