Bioinformatics Jobs in Boston

The Bioinformatics Capital - Kendall Square to Cambridge

25 open positions 15 companies hiring $145K avg salary

Why Work in Boston?

Boston stands as the undisputed leader in bioinformatics and computational biology, anchored by the dense concentration of biotech companies, research institutions, and hospitals in the Kendall Square/Cambridge corridor. Home to the Broad Institute, MIT, Harvard Medical School, and over 100 biotech companies, Boston offers unparalleled opportunities for bioinformatics professionals. The city's ecosystem uniquely combines academic excellence with commercial innovation, making it ideal for those seeking cutting-edge research or industry positions.

Market Overview

  • Highest concentration of bioinformatics jobs in the United States
  • Home to Broad Institute, the world's leading genomics research center
  • 100+ biotech companies within 5 miles of Kendall Square
  • Strong presence of major players: Moderna, Takeda, Biogen, Vertex
  • Excellent networking through Boston Bioinformatics Meetup and Harvard/MIT seminars
  • Top-tier academic institutions: MIT, Harvard, Tufts, BU, Northeastern
  • Vibrant startup scene with frequent funding and IPO activity

Top Biotech Companies in Boston

The Boston biotech ecosystem includes major companies like Mass General Brigham, Railway Health Inc, Formation Bio, Dana-Farber Cancer Institute, Pathai, and many emerging startups. Browse all companies →

Cost of Living

Boston ranks among the highest cost-of-living cities in the U.S., with median rent for a 1-bedroom apartment at $2,800-3,500/month in Cambridge/Kendall Square, and $2,200-2,800 in surrounding areas like Somerville or Brookline. However, bioinformatics salaries are correspondingly high, and the career growth opportunities often justify the cost. Public transportation (MBTA) is extensive, making car ownership optional.

Salary Ranges

See our Bioinformatics Salary Guide for detailed compensation data across all locations.

Bioinformatics Scientist I

$95K - $125K

Median: $110K

Bioinformatics Scientist II

$120K - $150K

Median: $135K

Senior Bioinformatics Scientist

$150K - $195K

Median: $172K

Principal Bioinformatics Scientist

$180K - $240K

Median: $210K

Computational Biologist

$110K - $145K

Median: $127K

Biostatistician

$105K - $140K

Median: $122K

Bioinformatics Engineer

$125K - $165K

Median: $145K

25 Bioinformatics Jobs in Boston

Data Scientist

Railway Health Inc
full-time 📅 Yesterday
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Data Scientist

Formation Bio 💰 $155K-$202K
full-time 📅 2d ago
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Associate Computational Biologist

Dana-Farber Cancer Institute 💰 $60K-$67K
research-scientist 📅 3d ago
View Job

Senior Pathologist

Pathai 💰 $208K-$320K
Hybrid full-time 📅 4d ago
View Job

Senior Software Engineer, Fullstack

Pathai 💰 $128K-$196K
Hybrid full-time 📅 4d ago
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Sr. Bioinformatics & ML Scientist

Nomic Bio
full-time 📅 1w ago
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Computational Biologist - Quantitative Methods & Target Discovery

Eli Lilly and Company 💰 $167K-$266K
Hybrid Full-time 📅 1w ago
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Data Scientist

Layer Health 💰 $180K-$200K
full-time 📅 1w ago
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Fall Co-op 2026, Computational Genomics (Gene Editing)

Vertex Pharmaceuticals 💰 $62K-$104K
Co-op 📅 2w ago
View Job

Executive Director, Biostatistics

Vertex Pharmaceuticals 💰 $236K-$354K
Hybrid Full-time 📅 2w ago
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Senior Director, Biostatistics

Formation Bio 💰 $311K-$385K
Hybrid Full-time 📅 2w ago
View Job

Associate Principal Scientist, Pharma R&D

Tempus AI 💰 $155K-$210K
Full-time 📅 2w ago
View Job

Scientist II, Computational Biology & AI

CRISPR Therapeutics 💰 $140K-$150K
Hybrid Full-time 📅 2w ago
View Job

Principal Data Scientist

Formation Bio 💰 $205K-$267K
full-time 📅 3w ago
View Job

Bioinformatics Software Engineer

Harvard University
research-scientist 📅 3w ago
View Job

Data Scientist II, Real World Evidence (RWE), Pharma R&D

Tempus AI 💰 $90K-$135K
full-time 📅 3w ago
View Job

Senior Data Scientist

Formation Bio 💰 $170K-$215K
full-time 📅 3w ago
View Job

Data Scientist Intern

Triple Ring Technologies 💰 $20K-$30K
full-time 📅 3w ago
View Job

Senior Principal DSX Data Scientist

Genentech 💰 $189K-$352K
full-time 📅 4w ago
View Job

Director, Biostatistics

Tango Therapeutics
full-time 📅 4w ago
View Job

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Frequently Asked Questions

Is Boston the best city for bioinformatics careers?

Boston consistently ranks #1 for bioinformatics opportunities due to its unique combination of top research institutions (Broad Institute, MIT, Harvard), major biotech companies (Moderna, Vertex, Takeda), and a thriving startup ecosystem. The density of opportunities, networking events, and career growth potential is unmatched.

What are the top bioinformatics companies in Boston?

Boston's top bioinformatics employers include Broad Institute, Moderna, Takeda, Vertex Pharmaceuticals, Biogen, Ginkgo Bioworks, Sanofi, Alnylam, Blueprint Medicines, and dozens of growing startups in Kendall Square and Cambridge.

How does Boston's bioinformatics salary compare to other cities?

Boston offers some of the highest bioinformatics salaries in the U.S., typically 10-20% higher than the national average. Senior scientists earn $150K-195K, and principal-level roles reach $180K-240K. While cost of living is high, the premium salaries and career acceleration make it financially competitive.

Do I need a PhD to work in bioinformatics in Boston?

Not necessarily. While many senior research roles prefer PhDs, there are abundant opportunities for Master's and Bachelor's degree holders, especially in bioinformatics engineering, data analysis, and pipeline development. Startups and smaller companies often value practical skills over credentials.

What's the bioinformatics startup scene like in Boston?

Boston has the most active bioinformatics startup ecosystem in the world, with hundreds of early-stage companies in precision medicine, drug discovery, diagnostics, and computational pathology. Funding is abundant, with frequent Series A-C rounds and IPO activity. Kendall Square alone hosts 50+ biotech startups.

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