Computational Biology & Healthtech Companies in France
A curated guide to France's small and mid-size healthtech and computational-biology companies — the AI-driven drug discovery, digital pathology and TechBio players building the field from Paris, from ~40-person research teams to scale-ups.
Compare what each team works on, their funding and size, and browse open computational roles. Looking beyond France? See all companies or computational biology jobs.
Owkin
AI Drug Discovery/Diagnostics
4 open roles"AI to Find the Right Treatment for Every Patient"
Aqemia
AI Drug Discovery
6 open roles"Inventing new drugs at scale with generative AI and deep physics"
Aqemia pairs generative AI with a statistical-mechanics ("deep physics") engine that predicts binding affinity without relying on experimental training data, letting it screen billions of molecules per week to design small-molecule and RNA-targeted drug candidates. The team spun out of the École Normale Supérieure in Paris in 2019 and runs its own discovery programs alongside partnerships with major pharmaceutical companies..
View Aqemia profile & jobs →Iktos
AI Drug Discovery
"AI and robotics for drug discovery"
Iktos builds deep-learning tools for small-molecule drug design. Its Makya platform uses generative models to design novel, synthesizable molecules optimized across multiple parameters, while Spaya plans retrosynthetic routes.
View Iktos profile →Bioptimus
AI Foundation Models for Biology
2 open roles"Building the first universal AI foundation model for biology"
Bioptimus trains large foundation models that learn across biological scales — from molecules and cells to tissues and whole organisms. Its H-optimus model, trained on hundreds of thousands of histopathology slides, is among the largest open-source pathology models; M-optimus extends this to a multimodal model integrating pathology, spatial transcriptomics and genomics.
View Bioptimus profile & jobs →SeqOne Genomics
Clinical Genomics / Bioinformatics SaaS
"Smarter genomics, faster insights, greater confidence"
SeqOne builds an AI-powered NGS bioinformatics platform used by clinical and research labs to analyze and interpret genomic data. Its tools — from the SeqOne Flow pipeline to the DiagAI variant-prioritization score and automated HRD testing — turn raw sequencing data into clinical-grade reports.
View SeqOne Genomics profile →Enterome
Microbiome Drug Discovery
"Microbiome decoded, healthcare transformed"
Enterome is a clinical-stage biotech whose drug discovery runs on computational biology: its Mimicry platform mines a proprietary database of 20+ million full-length gut-microbiome proteins with biocomputational tools and bioassays to find molecular mimics of tumor antigens, feeding an off-the-shelf immunotherapy pipeline (glioblastoma, lymphoma, colorectal). Founded in Paris in 2012 out of INRA's metagenomics platform..
View Enterome profile →Just across the border
A close neighbour worth knowing: SOPHiA GENETICS (Lausanne, Switzerland + Boston) runs one of the most widely used genomic-analytics platforms, SOPHiA DDM — larger and public, so it sits just outside this France / early-stage list. Looking wider? Browse all companies or see computational biology jobs.