Director, Head of Product Management – AI-Enabled Precision Medicine (Therapeutics & Innovations)

Director, Head of Product Management – AI-Enabled Precision Medicine (Therapeutics & Innovations)

About Us

We are redefining the future of precision medicine by integrating AI with healthcare to create next-generation, precision treatment modalities. Our multidisciplinary team is building products at the intersection of clinical data, multi-omics, and machine learning—unlocking entirely new approaches to drug development and patient care.

Within the Therapeutics & Innovations Business Unit, we are developing a new category that bridges diagnostics and therapeutics. Our platform combines deep scientific expertise with proprietary datasets to power AI-enabled solutions that can transform how therapies are discovered, developed, and deployed.

We are looking for a product leader who can translate this potential into real, scalable products—owning the strategy, roadmap, and execution to bring these innovations to market.

The Role

We are seeking aDirector / Head of Product Managementto lead product strategy and execution for our AI-enabled therapeutics platform. This is a highly cross-functional leadership role at the center of science, engineering, clinical development, and commercial strategy.

You will define what we build, why it matters, and how it creates value—for biopharma partners, clinicians, and ultimately patients. You will own the product lifecycle end-to-end: from concept and validation through development, launch, and iteration.

This role requires a rare blend ofscientific fluency, product rigor, and commercial instinct. You will work closely with R&D, AI, medical, business development, and marketing to ensure our products are scientifically credible, operationally feasible, and commercially compelling.

What You’ll Do

Product Strategy & Vision

• Define and own the product vision and roadmap for AI-enabled tools for precision medicine offerings (e.g., biomarkers, trial enablement tools, co-development platforms) via genomic language models, biomedical AI agents, AI-driven analysis platforms, forecasting algorithms.

• Identify high-value use cases across drug development (e.g., trial design, patient selection, translational insights, companion diagnostics).

• Translate platform capabilities into clear product strategies aligned with business goals.

Product Development & Execution

• Lead the end-to-end product lifecycle: concept → validation → build → launch → iteration.

• Partner with R&D, data science, and engineering to define product requirements and ensure high-quality execution.

• Drive prioritization decisions across competing opportunities based on impact, feasibility, and strategic alignment.

Customer & Market Insight

• Engage with biopharma partners, clinicians, and internal stakeholders to deeply understand needs and workflows.

• Synthesize customer insights into product requirements and roadmap decisions.

• Continuously assess market trends, competitive landscape, and emerging technologies.

Cross-Functional Leadership

• Serve as the central hub across Product, R&D, Clinical, BD, and Marketing.

• Align stakeholders around a unified product strategy and execution plan.

• Drive decision-making in a matrixed, fast-moving environment.

Commercialization & Launch

• Partner with commercial and BD teams to define product positioning, packaging, and pricing.

• Support go-to-market strategy, including pilot programs, partnerships, and scaled deployments.

• Ensure successful product launches with clear value propositions and supporting evidence.

Data, Evidence & Validation

• Define requirements for product validation, including analytical, clinical, and real-world evidence.

• Ensure products meet scientific, regulatory, and commercial expectations.

• Partner with clinical and regulatory teams to align product strategy with approval pathways where applicable.

Team Building & Leadership

• Build and mentor a high-performing product management function.

• Establish product processes, operating cadence, and best practices.

• Foster a culture of ownership, speed, and scientific rigor.

What We’re Looking For

• Advanced degree (PhD, MD, MS, or equivalent) in life sciences, bioengineering, computational biology, or related field preferred.

• 8–12+ years of experience in product management, product strategy, or related roles in biotech, life sciences, or healthcare technology.

• Proven track record of building and launching complex, data-driven products.

• Strong understanding of drug development workflows and/or clinical diagnostics.

• Experience working with AI/ML-driven products or data platforms is highly preferred.

• Exceptional ability to translate complex science into clear product decisions and strategies.

• Demonstrated success leading cross-functional teams in ambiguous environments.

• Strong commercial acumen, including product-market fit, pricing, and partnership models.

Bonus:

• Experience with biomarker development, oncology, or precision medicine.

• Background in diagnostics + therapeutics integration.

• Experience in early-stage or high-growth environments.

Why Join Us

• Build and define an entirely new category at the intersection of AI, diagnostics, and therapeutics.

• Own product strategy for some of the most advanced datasets and capabilities in healthcare.

• Work alongside world-class scientists, clinicians, and business leaders.

• Directly impact how therapies are developed and delivered to patients.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$184,600—$230,700 USD

Compensation & Total Rewards

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

• Annual performance incentive bonus

• Long-term equity awards

• Comprehensive health benefits (medical, dental, vision)

• 401(k) with company match