Bioinformatician II - Institute for Genomic Health

Mount Sinai Health Systems
Location
New York, NY
Job Type
Full-time
Posted
July 3, 2026
Views
9
Salary Range
$66k - $100k USD

Job Description

DescriptionMount Sinai, located in New York City, NY, is seeking an exceptional and motivated Bioinformatician with expertise in computational genomics and/or statistical genetics to support projects in the Institute for Genomic Health (IGH) at the Icahn School of Medicine at Mount Sinai. IGH is empowering multi-disciplinary research to accelerate the translation of insights from massive-scale genomic databases into routine clinical care for the benefit of patients from diverse populations. We seek a bioinformatician interested in working in a fast-paced, highly collaborative environment with interdisciplinary teams of genetic researchers, clinician scientists, data scientists, and disease area experts. The individual will demonstrate strong statistical and computational genomics programming proficiencies with proven expertise in genomic analysis and advanced knowledge of analytical methodologies.

Responsibilities - Performs statistical genetics analysis of large-scale datasets of human germline genomic datasets (genome sequencing and array) linked to patient health records to support genomic discovery and genomic risk prediction studies.

  • Generates analytical pipelines, tools, and best practices for genomic discovery in diverse and admixed populations
  • Documents analyses, creates summaries and presents written and verbal results to requestors.
  • Writes text for study reports and publications. Prepares analysis plans and methods used for incorporation in abstracts, manuscripts and grants.
  • Identifies potential data problems from analytic queries and takes appropriate actions to guide the resolution process.
  • Collaborates with principal investigators, co-investigators, sponsors and external representatives to ensure that project results and conclusions are presented accurately and without bias and to jointly achieve objectives and timelines.
  • Provides consultation to the clinical research project team on statistical issues related to the project.
  • Supports the clinical research team to identify potential data problems from analytic queries and to take appropriate action to guide the resolution process.
  • Performs other related duties as assigned.

Qualifications - M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.

  • 2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
  • Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor.

Employer DescriptionStrength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

DescriptionMount Sinai, located in New York City, NY, is seeking an exceptional and motivated Bioinformatician with expertise in computational genomics and/or statistical genetics to support projects in the Institute for Genomic Health (IGH) at the Icahn School of Medicine at Mount Sinai. IGH is empowering multi-disciplinary research to accelerate the translation of insights from massive-scale genomic databases into routine clinical care for the benefit of patients from diverse populations. We seek a bioinformatician interested in working in a fast-paced, highly collaborative environment with interdisciplinary teams of genetic researchers, clinician scientists, data scientists, and disease area experts. The individual will demonstrate strong statistical and computational genomics programming proficiencies with proven expertise in genomic analysis and advanced knowledge of analytical methodologies.

Responsibilities - Performs statistical genetics analysis of large-scale datasets of human germline genomic datasets (genome sequencing and array) linked to patient health records to support genomic discovery and genomic risk prediction studies.

  • Generates analytical pipelines, tools, and best practices for genomic discovery in diverse and admixed populations
  • Documents analyses, creates summaries and presents written and verbal results to requestors.
  • Writes text for study reports and publications. Prepares analysis plans and methods used for incorporation in abstracts, manuscripts and grants.
  • Identifies potential data problems from analytic queries and takes appropriate actions to guide the resolution process.
  • Collaborates with principal investigators, co-investigators, sponsors and external representatives to ensure that project results and conclusions are presented accurately and without bias and to jointly achieve objectives and timelines.
  • Provides consultation to the clinical research project team on statistical issues related to the project.
  • Supports the clinical research team to identify potential data problems from analytic queries and to take appropriate action to guide the resolution process.
  • Performs other related duties as assigned.

Qualifications - M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.

  • 2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
  • Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor.

Employer DescriptionStrength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $65885 - $100000 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The position is located in New York, NY at Mount Sinai Health Systems. The job posting does not specify a remote or hybrid work-mode policy, indicating it is an on-site role.
What are the required qualifications and experience for this role?
You need an M.S. in Bioinformatics, Computational Biology, Genomics, or a related computational field (Ph.D. preferred; Bachelor's with post-graduate experience considered). You also need 2+ years of post-graduate research experience manipulating large biological datasets, and advanced knowledge of genetics/statistical software like R, MatLab, or BioConductor.
What are the key responsibilities of the Bioinformatician II?
You will perform statistical genetics analysis on large-scale human genomic datasets, generate analytical pipelines for diverse populations, document and present results, write text for publications and grants, identify data problems, and collaborate with investigators and clinical research teams.
What is the salary range for this position?
The annual salary range for this role is $65,885 - $100,000. Actual salary depends on factors such as experience, education, and operational need, and does not include bonuses, differential pay, or other benefits.

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Remote Type: onsite
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Skills & Tags:
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