Principal AI Engineer - Evinova

AstraZeneca
AstraZeneca logo
Location
US - Cambridge Kendall SQ - MA
Job Type
Full-time
Posted
July 29, 2026
Views
2

Job Description

WHY JOIN US?

Evinova is a health-tech business focused on accelerating better health outcomes by advancing digital transformation across the life sciences sector. By combining science-based expertise, evidence-led rigor, and deep human insight, we design digital solutions that enable healthcare to work better for everyone.

Operating at the intersection of healthcare, technology, data, and analytics, we are helping unlock the full potential of digital health, transforming how clinical research is conducted, how care is delivered, and how patients experience healthcare. Our solutions are built to scale, driving efficiency, improving decision-making, and ultimately delivering better outcomes for patients worldwide.

At Evinova, we are driven by a shared purpose to transform health through data and digital innovation. Our teams collaborate across disciplines to solve complex challenges, continuously learning and evolving in a fast-paced, high-impact environment.

We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and team collaboration. To foster connection and collaboration,employees are expected to work from the office three days per week, creating opportunities for in-person teamwork, innovation, and meaningful connection.

Introduction to Role:

As Principal AI Engineer, you'll design and implement sophisticated agentic AI systems that power next-generation life sciences solutions. Working at the intersection of AI research and real-world healthcare applications, you'll build intelligent agents that can reason, plan, and act autonomously to solve complex clinical challenges.

What makes this role compelling:

  • Lead challenging projects in agentic AI, LLM orchestration, and multi-agent systems

  • Build AI agents that directly impact clinical trials, drug discovery, and ultimately patient care

  • Collaborate with product teams, clinical experts, and ML engineers in a fast-paced environment

  • Develop automated evaluation systems, prompt optimization techniques, and advanced agent architectures

  • Contribute to the AI in life sciences community through publications, conferences, and open-source work

Example impactful projects include:Intelligent AI agents for clinical document generation, advanced search systems for medical research, clinical trial optimization tools, synthetic patient data generation, and multi-modal healthcare AI assistants.

Accountabilities:

  • Design Advanced AI Systems

    • Build and deploy sophisticated agentic AI solutions using state-of-the-art LLMs

    • Develop novel approaches to agent memory, tool use, and multi-agent collaboration

    • Build sophisticated NLP systems for retrieval, information extraction, structured generation, graph reasoning.

  • Drive Technical Innovation

    • Create automated techniques for agent design, evaluation, and optimization

    • Systematically discover and validate effective prompt engineering approaches for agentic systems

    • Build specialized observability pipelines for continuous model and agent performance monitoring

  • Lead Cross-Functional Collaboration

    • Partner with product, design, and clinical teams to translate AI capabilities into impactful healthcare solutions

    • Mentor engineers and contribute to AI strategy across the organization

  • Contribute to the Field

    • Share expertise at conferences and through technical publications

    • Contribute to open-source projects and help advance best practices in healthcare AI

Essential Skills/ Experience:

  • Master's Degree in a relevant field (such as mathematics, computer science, data science).

WHY JOIN US?

Evinova is a health-tech business focused on accelerating better health outcomes by advancing digital transformation across the life sciences sector. By combining science-based expertise, evidence-led rigor, and deep human insight, we design digital solutions that enable healthcare to work better for everyone.

Operating at the intersection of healthcare, technology, data, and analytics, we are helping unlock the full potential of digital health, transforming how clinical research is conducted, how care is delivered, and how patients experience healthcare. Our solutions are built to scale, driving efficiency, improving decision-making, and ultimately delivering better outcomes for patients worldwide.

At Evinova, we are driven by a shared purpose to transform health through data and digital innovation. Our teams collaborate across disciplines to solve complex challenges, continuously learning and evolving in a fast-paced, high-impact environment.

We also recognize the importance of flexibility and balance. Our ways of working support both individual needs and team collaboration. To foster connection and collaboration,employees are expected to work from the office three days per week, creating opportunities for in-person teamwork, innovation, and meaningful connection.

Introduction to Role:

As Principal AI Engineer, you'll design and implement sophisticated agentic AI systems that power next-generation life sciences solutions. Working at the intersection of AI research and real-world healthcare applications, you'll build intelligent agents that can reason, plan, and act autonomously to solve complex clinical challenges.

What makes this role compelling:

  • Lead challenging projects in agentic AI, LLM orchestration, and multi-agent systems

  • Build AI agents that directly impact clinical trials, drug discovery, and ultimately patient care

  • Collaborate with product teams, clinical experts, and ML engineers in a fast-paced environment

  • Develop automated evaluation systems, prompt optimization techniques, and advanced agent architectures

  • Contribute to the AI in life sciences community through publications, conferences, and open-source work

Example impactful projects include:Intelligent AI agents for clinical document generation, advanced search systems for medical research, clinical trial optimization tools, synthetic patient data generation, and multi-modal healthcare AI assistants.

Accountabilities:

  • Design Advanced AI Systems

    • Build and deploy sophisticated agentic AI solutions using state-of-the-art LLMs

    • Develop novel approaches to agent memory, tool use, and multi-agent collaboration

    • Build sophisticated NLP systems for retrieval, information extraction, structured generation, graph reasoning.

  • Drive Technical Innovation

    • Create automated techniques for agent design, evaluation, and optimization

    • Systematically discover and validate effective prompt engineering approaches for agentic systems

    • Build specialized observability pipelines for continuous model and agent performance monitoring

  • Lead Cross-Functional Collaboration

    • Partner with product, design, and clinical teams to translate AI capabilities into impactful healthcare solutions

    • Mentor engineers and contribute to AI strategy across the organization

  • Contribute to the Field

    • Share expertise at conferences and through technical publications

    • Contribute to open-source projects and help advance best practices in healthcare AI

Essential Skills/ Experience:

  • Master's Degree in a relevant field (such as mathematics, computer science, data science).

  • 4+ years of industry experience in applied machine learning, with a strong focus on deep learning, NLP, and generative AI.

  • Extensive prior experience exploring and testing language model behavior, prompting and building products with language models.

  • Expert knowledge of Python and advanced ML/LLM frameworks (e.g., TensorFlow, PyTorch, Google ADK, Crewai,  LangChain, LlamaIndex)

  • Extensive experience with AWS services (e.g. SageMaker, Bedrock, MSK, EKS, ECS, OpenSearch).

  • Deep understanding of agentic AI systems and frameworks (e.g. agentic design patterns, multi-agent systems, reinforcement learning).

  • Excellent communication skills with the ability to articulate complex technical concepts to both technical and non-technical audiences

Desirable Skills/ Experience:

  • Ph.D. in a relevant field (such as mathematics, computer science, data science).

  • Demonstrated technical leadership experience, including successful delivery of large-scale AI projects.

  • Experience developing complex agentic systems using LLMs.

  • Experience with low-level languages used for implementing high-performance ML code (C/C++, Rust, CUDA, etc.)

  • Contributions to open-source AI projects or development of proprietary AI frameworks.

  • Expertise in areas such as few-shot learning, meta-learning, explainable AI.

  • Experience with AI ethics, responsible AI practices, and navigating regulatory landscapes for AI deployment in the life science industry.

SO, WHAT’S NEXT?

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

Where can I find out more?

Apply today to bring smarter, faster clinical trials to life!

Evinova is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. Evinova is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailingAZCHumanResources@astrazeneca.com.

#LI-Hybrid

The annual base pay for this position ranges from$144,648.80 - $189,851.55USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.

In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

28-Jul-2026

Closing Date

06-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Researching AstraZeneca before you apply?

See 35 open roles · Verified H-1B salary data · Clinical-trial hiring momentum · Culture, benefits & locations.

View AstraZeneca profile

Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The position is located in US - Cambridge Kendall SQ - MA. It is a hybrid role, and employees are expected to work from the office three days per week.
What are the required qualifications and experience level for this role?
You need a Master's Degree in a relevant field (e.g., mathematics, computer science, data science) and 4+ years of industry experience in applied machine learning, focusing on deep learning, NLP, and generative AI. You must also have extensive experience with language models, Python, advanced ML/LLM frameworks, AWS services, and agentic AI systems.
What are the key responsibilities of the Principal AI Engineer?
You will design and deploy sophisticated agentic AI systems and NLP solutions, drive technical innovation through automated evaluation and prompt engineering, partner with cross-functional teams to translate AI capabilities into healthcare solutions, mentor engineers, and contribute to the AI community through publications and open-source projects.
What is the salary range for this position?
The annual base pay for this position ranges from $144,648.80 to $189,851.55 USD, depending on factors such as market location, job-related knowledge, skills, and experience.
What benefits and compensation incentives are offered?
Benefits include a 401(k) retirement program, paid vacation, holidays, and leaves, alongside medical, prescription drug, dental, and vision coverage. Additionally, this position offers a short-term incentive bonus opportunity and eligibility to participate in an equity-based long-term incentive program.
How do I apply, and what is the application deadline?
You must complete the full application on the company's website. The job posting was published on July 28, 2026, and the closing date for applications is August 6, 2026.

Ready to Apply?

Apply for this Position

You'll be redirected to the company's application page

Share this job:

Explore AstraZeneca

Research the company before you apply.

  • 35 open roles
  • Verified H-1B salary data
  • Clinical-trial hiring momentum
  • Culture, benefits & locations
View company profile

Job Information

Source: workday
AI Relevance: 85/100 (Highly relevant)
Remote Type: onsite
Allowed Locations: US - Cambridge Kendall SQ - MA
Skills & Tags:
astrazeneca pharma

Get Similar Jobs by Email

Weekly digest of AstraZeneca and similar companies. Free.

Related Jobs

Apply for this Position

Get weekly job alerts