Bioinformatics Scientist

Guidehouse
Location
US - NC, Durham
Job Type
Full-time
Posted
August 8, 2026
Views
6

Job Description

Job Family

Scientist

Travel Required

None

Clearance Required

Ability to Obtain Public Trust

What You Will Do

We are looking for a Bioinformatics Scientist to support the operational objectives of the National Institute of Environmental Health Sciences (NIEHS) through advanced genomic data analysis, bioinformatics programming, and computational biology support. This position is a full-time position located in Research Triangle Park, NC and is telework eligible.

Analyze NGS, GWAS, genomic, biological, epidemiology, and population-based datasets, including ChIP-Seq, RNA-Seq, miRNA-Seq, SNP/structural variation discovery, imputation, stratification, haplotype, pathway, principal component, meta-analysis, and related statistical analyses.

  • Interpret genomic and targeted population study data, associated metadata, gene expression, exon, tiling, promoter, microarray, and multi-platform results to extract biologically meaningful insights.
  • Develop, implement, deploy, and maintain bioinformatics workflows, custom programs, utility scripts, macros, algorithms, analytical tools, and computational processes supporting experimental design, quality analysis, genome/metagenome integration, and biological discovery.
  • Use commercial software, freeware, custom-developed solutions, and high-performance computing environments to support scientific objectives, maintain workstations, and identify relevant analytical software solutions.
  • Collaborate with biologists, statisticians, bioinformaticians, investigators, and research teams to design analytical models, support data collection and experimental activities, and participate in scientific programming, laboratory, and interdisciplinary meetings.
  • Prepare reports, protocols, technical documentation, publication-quality graphics, and deliverables supporting NGS analyses, GWAS studies, statistical analyses, workflow development, publications, training activities, and scientific presentations.
  • Present findings to investigators, bioinformatics teams, study groups, and external audiences, and develop and deliver bioinformatics training materials, presentations, tutorials, and short-course instruction.

What You Will Need

  • Master's degree in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, Mathematics, Computer Science, Environmental Science, Microbiology, Molecular Biology, or related scientific discipline.
  • Minimum of FIVE (5) years of experience in bioinformatics, computational biology, biostatistics, genomics, or a related field.
  • Hands-on background analyzing next-generation sequencing data and genomic datasets.
  • Working knowledge of Genome-Wide Association Studies (GWAS).
  • Background performing bulk RNA sequencing analysis.
  • Skilled in conducting microbiome, phylogenetic, multi-omics, microarray, and cluster analyses.
  • Ability to work with large and complex biological datasets.
  • Proven ability to develop bioinformatics pipelines and analytical workflows.
  • Proficiency with R, Python, MATLAB, Perl, Shell scripting, Unix/Linux environments, and Java.
  • Demonstrated ability to collaborate with multidisciplinary scientific teams.
  • Ability to prepare technical reports, scientific documentation, and publication-quality visualizations.
  • Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What Would Be Nice To Have

  • Ph.D. in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, or a related scientific discipline.
  • Background supporting federal biomedical or environmental health research programs.
  • Strong written and verbal communication skills, including presentation experience.

Job Family

Scientist

Travel Required

None

Clearance Required

Ability to Obtain Public Trust

What You Will Do

We are looking for a Bioinformatics Scientist to support the operational objectives of the National Institute of Environmental Health Sciences (NIEHS) through advanced genomic data analysis, bioinformatics programming, and computational biology support. This position is a full-time position located in Research Triangle Park, NC and is telework eligible.

Analyze NGS, GWAS, genomic, biological, epidemiology, and population-based datasets, including ChIP-Seq, RNA-Seq, miRNA-Seq, SNP/structural variation discovery, imputation, stratification, haplotype, pathway, principal component, meta-analysis, and related statistical analyses.

  • Interpret genomic and targeted population study data, associated metadata, gene expression, exon, tiling, promoter, microarray, and multi-platform results to extract biologically meaningful insights.
  • Develop, implement, deploy, and maintain bioinformatics workflows, custom programs, utility scripts, macros, algorithms, analytical tools, and computational processes supporting experimental design, quality analysis, genome/metagenome integration, and biological discovery.
  • Use commercial software, freeware, custom-developed solutions, and high-performance computing environments to support scientific objectives, maintain workstations, and identify relevant analytical software solutions.
  • Collaborate with biologists, statisticians, bioinformaticians, investigators, and research teams to design analytical models, support data collection and experimental activities, and participate in scientific programming, laboratory, and interdisciplinary meetings.
  • Prepare reports, protocols, technical documentation, publication-quality graphics, and deliverables supporting NGS analyses, GWAS studies, statistical analyses, workflow development, publications, training activities, and scientific presentations.
  • Present findings to investigators, bioinformatics teams, study groups, and external audiences, and develop and deliver bioinformatics training materials, presentations, tutorials, and short-course instruction.

What You Will Need

  • Master's degree in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, Mathematics, Computer Science, Environmental Science, Microbiology, Molecular Biology, or related scientific discipline.
  • Minimum of FIVE (5) years of experience in bioinformatics, computational biology, biostatistics, genomics, or a related field.
  • Hands-on background analyzing next-generation sequencing data and genomic datasets.
  • Working knowledge of Genome-Wide Association Studies (GWAS).
  • Background performing bulk RNA sequencing analysis.
  • Skilled in conducting microbiome, phylogenetic, multi-omics, microarray, and cluster analyses.
  • Ability to work with large and complex biological datasets.
  • Proven ability to develop bioinformatics pipelines and analytical workflows.
  • Proficiency with R, Python, MATLAB, Perl, Shell scripting, Unix/Linux environments, and Java.
  • Demonstrated ability to collaborate with multidisciplinary scientific teams.
  • Ability to prepare technical reports, scientific documentation, and publication-quality visualizations.
  • Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What Would Be Nice To Have

  • Ph.D. in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, or a related scientific discipline.
  • Background supporting federal biomedical or environmental health research programs.
  • Strong written and verbal communication skills, including presentation experience.
  • Ability to develop custom bioinformatics applications and advanced computational algorithms.
  • Familiarity supporting high-performance computing environments.
  • Ability to provide bioinformatics training, mentoring, and instructional support.
  • Demonstrated contributions to scientific manuscripts and peer-reviewed publications.
  • Collaboration across interdisciplinary genomic, epidemiologic, and population-based research programs.

What We Offer

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include

  • Medical, Rx, Dental & Vision Insurance
  • Personal and Family Sick Time & Company Paid Holidays
  • Parental Leave
  • 401(k) Retirement Plan
  • Group Term Life and Travel Assistance
  • Voluntary Life and AD&D Insurance
  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
  • Transit and Parking Commuter Benefits
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
  • Employee Referral Program
  • Corporate Sponsored Events & Community Outreach
  • Care.com annual membership
  • Employee Assistance Program
  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
  • Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com.  Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse.  Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The position is located in Durham, North Carolina (specifically Research Triangle Park, NC) and is telework eligible.
What are the required qualifications and experience level for this role?
You need a Master's degree in Bioinformatics, Biostatistics, Computational Biology, or a related scientific discipline, and at least five years of experience in bioinformatics, computational biology, biostatistics, or genomics. You must also have hands-on experience with NGS data, GWAS, bulk RNA sequencing, and proficiency in R, Python, MATLAB, Perl, Shell, Unix/Linux, and Java.
What are the key responsibilities of the Bioinformatics Scientist?
You will analyze NGS, GWAS, genomic, biological, epidemiology, and population-based datasets. You will also develop and maintain bioinformatics workflows, collaborate with interdisciplinary research teams, prepare technical reports and publication-quality graphics, and deliver bioinformatics training materials.
What benefits does Guidehouse offer for this position?
Benefits include medical, dental, vision, and Rx insurance; 401(k) retirement plan; parental leave; personal and family sick time; paid holidays; short-term and long-term disability; tuition reimbursement; Care.com membership; and commuter benefits. The position may also be eligible for a discretionary variable incentive bonus.

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Job Information

Source: manual
AI Relevance: 95/100 (Highly relevant)
Remote Type: onsite
Allowed Locations: Worldwide
Skills & Tags:
guidehouse bioinformatics computational biology genomics GWAS biostatistics multi-omics

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