Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)
Job Description
#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal Scientist
Location: Cambridge, MANovartis is a leader in neuroscience and cardiovascular disease areas with a robust and diverse pipeline of innovative therapies. We are seeking a translational modeler eager to accelerate oligonucleotide therapeutics (xRNA”), including antibody-xRNA conjugates, from discovery through clinical translation.
In this role, you will partner with multi-disciplinary discovery and preclinical teams to develop and apply model-informed approaches that shape program strategies.
As part of a truly translational modeling team, you will also work closely with clinical pharmacology and pharmacometrics groups to support clinical programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key decisions from early dose optimization through life-cycle management.
This role reports to a Modeling and Simulation (M&S) team lead within the Pharmacokinetic Sciences (PKS) M&S team.
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