Associate Principal Scientist, Translational Research

Tempus AI
Location
Chicago
Job Type
Full-time
Posted
August 28, 2026
Views
16

Job Description

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Responsibilities

● Partner with our pharma clients to design, develop and execute computational research projects leveraging

the Tempus platform to advance precision medicine research programs.

● Analyze and integrate large diverse clinical and molecular datasets to extract insights and drive new research

opportunities.

● Stay ahead of research and industry trends in oncology drug development, and identify specific areas where

the Tempus platform can establish new markets.

● Become an expert in our biopharma partners’ strategy, pipeline and portfolio to proactively determine all

areas that the Tempus platform could add value to the drug development process of our partners.

● Develop and drive global account strategy in coordination with the account team.

● Document, summarize and communicate highly technical results and methods clearly to non-technical

audiences.

● Work directly with clients to co-architect solutions and projects that leverage the Tempus platform to solve

customers' challenges and maintain R&D relationships as the trusted technical advisor.

● Author whitepapers and illustrate the value of multimodal analysis and AI in drug discovery in coordination

with our Research, Engineering & Data Science teams.

● Work with Product and Engineering teams to streamline workflow of computational analyze

● Contribute to the development of the portfolio by providing feedback to leadership regarding client

responses and suggestions; maintain a solution-oriented mindset.

● Track progress against defined strategic objectives and goals; review progress/setbacks frequently wi

broader Account Team and Tempus leadership.

● Travel approximately 25% of working time, domestically and internationally.

Preferred Qualification

● PhD degree in a quantitative discipline (e.g. Biostatistics/Statistical Genetics, Cancer Genetics,

Bioinformatics, Computational Biology, Computational Immunology or similar). Alternatively, a PhD in

Molecular Biology or Immunology combined with a very strong record of computational biology.

● Minimum 4+ years in drug development leveraging genomic and multimodal data for drug discovery and

development .

● Strong understanding of molecular data and artificial intelligence in drug discovery with experience

integrative modeling of multi-modal clinical and omics data.

● Proficient in R, Python, and SQ

● Previous experience working with large transcriptome data sets.

● Strong understanding of Cancer, Immunology, Clinical Trials and Real World Evidence Platforms .

● Prior consulting and/or client facing experience is highly desirable

● Thrive in a fast-paced environment and willing to shift priorities seamlessly.

Preferred Experience

● Proven track record of developing solutions utilizing molecular and multimodal data.

● Demonstrated ability to influence without authority (both with internal and external stakeholders

● Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and

external stakeholders to quickly solve problems

● Experience with communicating insights and presenting concepts to diverse audiences.

● Strong peer-reviewed publication record.

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Responsibilities

● Partner with our pharma clients to design, develop and execute computational research projects leveraging

the Tempus platform to advance precision medicine research programs.

● Analyze and integrate large diverse clinical and molecular datasets to extract insights and drive new research

opportunities.

● Stay ahead of research and industry trends in oncology drug development, and identify specific areas where

the Tempus platform can establish new markets.

● Become an expert in our biopharma partners’ strategy, pipeline and portfolio to proactively determine all

areas that the Tempus platform could add value to the drug development process of our partners.

● Develop and drive global account strategy in coordination with the account team.

● Document, summarize and communicate highly technical results and methods clearly to non-technical

audiences.

● Work directly with clients to co-architect solutions and projects that leverage the Tempus platform to solve

customers' challenges and maintain R&D relationships as the trusted technical advisor.

● Author whitepapers and illustrate the value of multimodal analysis and AI in drug discovery in coordination

with our Research, Engineering & Data Science teams.

● Work with Product and Engineering teams to streamline workflow of computational analyze

● Contribute to the development of the portfolio by providing feedback to leadership regarding client

responses and suggestions; maintain a solution-oriented mindset.

● Track progress against defined strategic objectives and goals; review progress/setbacks frequently wi

broader Account Team and Tempus leadership.

● Travel approximately 25% of working time, domestically and internationally.

Preferred Qualification

● PhD degree in a quantitative discipline (e.g. Biostatistics/Statistical Genetics, Cancer Genetics,

Bioinformatics, Computational Biology, Computational Immunology or similar). Alternatively, a PhD in

Molecular Biology or Immunology combined with a very strong record of computational biology.

● Minimum 4+ years in drug development leveraging genomic and multimodal data for drug discovery and

development .

● Strong understanding of molecular data and artificial intelligence in drug discovery with experience

integrative modeling of multi-modal clinical and omics data.

● Proficient in R, Python, and SQ

● Previous experience working with large transcriptome data sets.

● Strong understanding of Cancer, Immunology, Clinical Trials and Real World Evidence Platforms .

● Prior consulting and/or client facing experience is highly desirable

● Thrive in a fast-paced environment and willing to shift priorities seamlessly.

Preferred Experience

● Proven track record of developing solutions utilizing molecular and multimodal data.

● Demonstrated ability to influence without authority (both with internal and external stakeholders

● Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and

external stakeholders to quickly solve problems

● Experience with communicating insights and presenting concepts to diverse audiences.

● Strong peer-reviewed publication record.

● Experience with: Pandas, NumPy, SciPy, Scikit-learn, Jupyter Notebooks, RStudio, tidyverse, ggplot, Git,

matplotlib, seaborn, HTML5, CSS3, JavaScript, D3, Plot.ly, Flask, Dask, Docker, AWS.

● Team player mindset and ability to work in an interdisciplinary team.

● Goal orientation, self motivation, and drive to make a positive impact in healthcare.

The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The position is located in Chicago. The provided text does not specify whether the work-mode policy is remote, hybrid, or on-site.
What are the key responsibilities of this role?
You will partner with pharma clients to design and execute computational research projects, analyze large clinical and molecular datasets, develop global account strategies, communicate technical results to non-technical audiences, and collaborate with Product and Engineering teams. This role requires approximately 25% domestic and international travel.
What qualifications and experience are preferred?
You should have a PhD in a quantitative discipline (or Molecular Biology/Immunology with strong computational experience) and 4+ years in drug development leveraging genomic and multimodal data. Proficiency in R, Python, SQL, and experience with large transcriptome datasets, cancer, immunology, clinical trials, and real-world evidence platforms are also preferred.
What benefits does the company offer?
Tempus offers a full range of benefits depending on the position, which may include incentive compensation, restricted stock units, medical benefits, and other benefits.

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Job Information

Source: manual
AI Relevance: 82/100 (Highly relevant)
Remote Type: onsite
Allowed Locations: Worldwide
Skills & Tags:
tempus artificial intelligence bioinformatics computational biology statistical genetics drug discovery data science biostatistics immunology oncology

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