Director / Senior Director, Research Engineering, Life Sciences AI

Lilasciences
Location
San Francisco, CA USA
Job Type
Full-time
Posted
September 2, 2026
Views
1

Job Description

Your Impact at LILA

LSAI (Life Sciences Artificial Intelligence) is building the computational platform that powers Lila's work in the life sciences. We are looking for a Research Engineer to own and build the core codebase that our models plug into, the foundation on which our scientists build and ship their work. This role is part of the LSAI leadership team and reports to the SVP of Generative Biology.

This role combines deep hands-on IC work with growing management responsibility. You will personally architect and build the core platform while also building and leading a team as headcount grows. IC contribution remains the top priority for this role.

What You'll Be Building

  • Design, build, and own the foundation of the LSAI codebase, the core infrastructure that scientist-owned models plug into.
  • Set and enforce engineering standards for code quality, testing, versioning, documentation, and repository structure.
  • Make architectural decisions that balance rigor with the reality that most contributors are scientists first, engineers second.
  • Anticipate infrastructure bottlenecks and define the platform roadmap to enable rapid iteration while maintaining quality and reproducibility.
  • Build and manage an engineering team over time while remaining a primary hands-on contributor.

What You'll Need to Succeed

  • Strong track record designing and building core software platforms or frameworks that scientists and engineers depend on.
  • Deep platform architecture expertise, with biological applications such as protein design, nucleic-acid design, or cell foundation models as a plus.
  • Experience building infrastructure and tooling alongside scientists in a research environment without sacrificing velocity.
  • Full ML lifecycle expertise across data, training, evaluation, and MLOps, with a track record of taking research code to production.
  • Comfort shifting between hands-on building and strategic leadership without letting either crowd out the other.
  • Experience mentoring people and setting technical practices across a team or organization, beyond individual output.

Bonus Points For

  • Experience in a bioML lab or scientific computing environment.
  • Familiarity with or curiosity about computational biology, protein modeling, or ML-adjacent codebases.
  • Comfort working around model builders, even if you do not build the models yourself.
  • Performance engineering experience, including profiling and optimizing training and inference.
  • Experience writing or tuning CUDA or Triton kernels.
  • Ability to reason about GPU utilization, MFU/HFU, memory bandwidth, and kernel-level bottlenecks.
  • Deep expertise in the modern ML systems stack, including PyTorch internals, mixed precision, and distributed training across multi-GPU or multi-node clusters.

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits.Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits.Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range

$320,000—$490,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

Your Impact at LILA

LSAI (Life Sciences Artificial Intelligence) is building the computational platform that powers Lila's work in the life sciences. We are looking for a Research Engineer to own and build the core codebase that our models plug into, the foundation on which our scientists build and ship their work. This role is part of the LSAI leadership team and reports to the SVP of Generative Biology.

This role combines deep hands-on IC work with growing management responsibility. You will personally architect and build the core platform while also building and leading a team as headcount grows. IC contribution remains the top priority for this role.

What You'll Be Building

  • Design, build, and own the foundation of the LSAI codebase, the core infrastructure that scientist-owned models plug into.
  • Set and enforce engineering standards for code quality, testing, versioning, documentation, and repository structure.
  • Make architectural decisions that balance rigor with the reality that most contributors are scientists first, engineers second.
  • Anticipate infrastructure bottlenecks and define the platform roadmap to enable rapid iteration while maintaining quality and reproducibility.
  • Build and manage an engineering team over time while remaining a primary hands-on contributor.

What You'll Need to Succeed

  • Strong track record designing and building core software platforms or frameworks that scientists and engineers depend on.
  • Deep platform architecture expertise, with biological applications such as protein design, nucleic-acid design, or cell foundation models as a plus.
  • Experience building infrastructure and tooling alongside scientists in a research environment without sacrificing velocity.
  • Full ML lifecycle expertise across data, training, evaluation, and MLOps, with a track record of taking research code to production.
  • Comfort shifting between hands-on building and strategic leadership without letting either crowd out the other.
  • Experience mentoring people and setting technical practices across a team or organization, beyond individual output.

Bonus Points For

  • Experience in a bioML lab or scientific computing environment.
  • Familiarity with or curiosity about computational biology, protein modeling, or ML-adjacent codebases.
  • Comfort working around model builders, even if you do not build the models yourself.
  • Performance engineering experience, including profiling and optimizing training and inference.
  • Experience writing or tuning CUDA or Triton kernels.
  • Ability to reason about GPU utilization, MFU/HFU, memory bandwidth, and kernel-level bottlenecks.
  • Deep expertise in the modern ML systems stack, including PyTorch internals, mixed precision, and distributed training across multi-GPU or multi-node clusters.

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits.Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits.Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range

$320,000—$490,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with ourCandidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The position is located in San Francisco, CA USA. The job posting does not specify a remote, hybrid, or on-site work-mode policy, though it mentions commuter benefits and a subsidized lunch program for office-based employees.
What are the key responsibilities of this role?
You will design, build, and own the foundation of the LSAI codebase and core infrastructure. You will set engineering standards, make architectural decisions, anticipate infrastructure bottlenecks, and build and manage an engineering team over time while remaining a primary hands-on contributor.
What qualifications and experience do I need to apply?
You need a strong track record of building core software platforms, deep platform architecture expertise, and experience working alongside scientists in research environments. You also need full ML lifecycle expertise (data, training, evaluation, MLOps) and experience mentoring people and setting technical practices.
What is the salary range for this position?
The expected base salary range for this U.S.-based position is $320,000 to $490,000 USD. You may also receive bonus potential and early-stage equity.
What benefits does the company offer?
U.S. benefits include medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off and holidays; paid parental leave; educational assistance; commuter benefits (including bike share memberships); and a subsidized lunch program. International benefits are tailored by region.
Who will I report to in this role?
This role is part of the LSAI leadership team and reports directly to the SVP of Generative Biology.

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Job Information

Source: greenhouse
AI Relevance: 92/100 (Highly relevant)
Remote Type: onsite
Allowed Locations: San Francisco, CA USA
Skills & Tags:
AI

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