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Revolution Medicines

Targeting RAS-addicted cancers with next-generation precision oncology

Redwood City, CA
550+

Machine learning & AI jobs at Revolution Medicines

Revolution Medicines has 4 open machine learning, AI and data science roles on CompBioJobs.

About Revolution Medicines

Industry: Precision Oncology / Clinical-Stage Biotech
Founded: 2014
Founders: Mark Goldsmith, Jack Leff
Status: Public (Nasdaq: RVMD)

Funding & Growth

Total Raised: $2.5B+
Valuation: ~$3.5B market cap
Stage: Public (Nasdaq: RVMD)
Key Investors:
ARCH Venture Partners Foresite Capital Public markets

✓ Pros

  • • Compelling RAS oncology science with best-in-class pipeline (RMC-6236, RMC-9805)
  • • Competitive compensation with published salary bands
  • • Hybrid work model at Redwood City HQ
  • • Strong clinical-stage momentum — multiple programs in Phase 1/2
  • • Collaborative culture bridging computational and clinical teams

✗ Cons

  • • Clinical-stage risk — pipeline still in Phase 1/2
  • • Redwood City location (limited remote options for most roles)
  • • Biostatistics and clinical data science focus — fewer pure ML/AI roles than TechBio peers
  • • Smaller computational biology team relative to large pharma

🏢 Working Here

Revolution Medicines is a clinical-stage precision oncology company in Redwood City, CA, focused exclusively on RAS-addicted cancers — a notoriously difficult target class that includes KRAS-mutant pancreatic, lung, and colorectal cancers.

The company pioneered RAS(ON) inhibitors that target the active GTP-bound form of RAS, setting it apart from earlier KRASG12C(OFF) inhibitors like sotorasib and adagrasib.

With multiple programs in the clinic (RMC-6236, RMC-9805, RMC-6291) and a public listing on Nasdaq (RVMD), RevMed offers the scientific focus of a biotech startup with the resources and process rigor of a company approaching late-phase trials.

The data science organization spans biostatistics, statistical programming, exploratory data science, and clinical data management — all supporting a pipeline that is advancing rapidly toward potential registration.

🧬 Bioinformatics Focus

Computational work at Revolution Medicines centers on clinical-stage biostatistics and data science rather than early discovery.

Roles include statisticians designing and analyzing oncology trials (early and late phase), statistical programmers building CDISC-compliant SDTM/ADaM datasets and regulatory submissions, exploratory data scientists applying ML and causal inference to clinical trial and real-world data, and clinical data managers overseeing EDC and data quality.

The company is building out more advanced modeling capabilities — survival analysis, Bayesian methods, causal inference, HEOR — as its pipeline matures toward registration-enabling studies.

Strong SAS and R skills are essential; Python and ML experience are valued for the Exploratory Data Science group.

📈 Career Growth & Development

Career Paths

Biostatistics Track

Associate Director, Biostatistics → Director, Biostatistics → Senior Director, Biostatistics → VP, Biostatistics

Statistical Programming Track

Associate Principal Statistical Analyst → Principal Statistical Analyst → Associate Director, Statistical Programming → Director, Statistical Programming

Data Science Track

Associate Director, Medical Analytics & EDS → Director, Medical Analytics & EDS → Senior Director, Data Science
💰

Compensation

Published salary bands: Associate Director $186K–$233K, Director $211K–$264K, Senior Director $244K–$305K. RSUs and annual bonuses included.

🚀

Pipeline Momentum

Multiple programs advancing rapidly — early hires can grow into regulatory-submission leadership roles faster than at large pharma.

🔬

Science

Work directly on RAS(ON) programs addressing the most common oncogenic mutations (KRASG12D, G12C) in pancreatic, lung, and colorectal cancer.

🤝

Cross-functional Exposure

Strong collaboration across clinical development, medical affairs, and regulatory — broad visibility for quantitative scientists.

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