Vertex Pharmaceuticals
Creating Transformative Medicines
Machine learning & AI jobs at Vertex Pharmaceuticals
Vertex Pharmaceuticals has 6 open machine learning, AI and data science roles on CompBioJobs. Across 6 of its AI/ML postings that state pay, the typical posted range is $167K–$251K.
- Senior Director, ICX Data, Analytics & AI · Boston, MA
- Senior Principal AI Platform Engineer, Data & AI Platform · Boston, MA
- Senior Principal AI Engineer · Boston, MA
- Scientific Fellow, Agentic AI (AI Co-Scientist Lead) · Boston, MA
- Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery · Boston, MA
- Principal Full Stack AI Engineer · Boston, MA
About Vertex Pharmaceuticals
Funding & Growth
✓ Pros
- • CF drug success story
- • Strong financials
- • Boston Seaport location
- • Excellent benefits
- • Gene editing programs
✗ Cons
- • High expectations
- • CF franchise dependency
- • Competitive to get into
- • Fast-paced environment
Open Positions (31)
Research Scientist, Analytical Development – Functional Genomics & Multi-omics
Spring Co-Op 2027, In Silico Modeling
Real World Principal Biostatistician
Spring 2027 Co-op, Functional Genomics
Spring Co-Op 2027, Process Engineering Data Analytics
Senior Director, ICX Data, Analytics & AI
Senior Biostatistician II
Vertex Spring Co-Op 2027, Analytical Development, Statistics
Advanced Analytics Associate Director - Kidney
Vertex Spring Co-Op 2027, Long Read Sequencing
Real World Evidence Associate Director
Real World Evidence Manager
Modeling & Simulations Associate Director
Senior Principal AI Platform Engineer, Data & AI Platform
Director, Knowledge Graph & Semantics - HYBRID ROLE
Director, Agent Intelligence - HYBRID ROLE
Senior Principal Scientist, Agentic Systems Development for Drug Discovery
Principal Biostatistician
Senior Principal AI Engineer
Sr. Biostatistician II
Principal Programmer, Statistical Programming (Remote)
Computational Chemistry Principal Research Scientist (Computational Drug Design)
CMC Statistics Director
Scientific Fellow, Agentic AI (AI Co-Scientist Lead)
Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery
Executive Director, Data & Methods (Data and Computational Sciences)
Principal Full Stack AI Engineer
Computational Genomics Senior Research Scientist
Director, Biostatistics
Executive Director, Biostatistics
Biostatistics Associate Director (HYBRID)
Hiring Signals
Open roles from our DB joined with public DOL H1B LCA filings (FY2026 Q1, Oct–Dec 2025).
Salary & hiring signal, not a forecast. Use these figures as a reference for recent compensation bands and H1B-sponsorship activity at Vertex Pharmaceuticals — they don't predict future H1B willingness or guarantee similar wages on new offers.
Scope: H1B LCA filings cover all roles at Vertex Pharmaceuticals (engineering, science, IT, etc.) — not bioinformatics-only. At biotech & pharma companies the mix skews toward R&D and computational roles, but treat the wage distribution as the company's overall H1B band rather than a strict comp-bio benchmark.
Open Roles (Live)
31Concentrated in Boston (29/31 roles).
H1B Wages — Q1 2026
30 petitions filedAverage: $147K — actual filed wages from H1B LCA disclosures, not job-board self-reports.
Median $151K across 30 filings; expect offers to vary by team and seniority.
Seniority Mix (Wage Levels)
DOL prevailing wage tiers (L1 entry → L4 expert). Note: companies sometimes file senior roles at lower tiers to reduce prevailing-wage obligations — L1/L2 doesn't always mean junior position.
Filed mostly at L3/L4 (76%) — upper wage tiers dominate.
Historical H1B trend chart coming — backfilling Q2/Q3/Q4 2025 LCA data.
Clinical-Trial Portfolio
Trend: StableData updated May 9, 2026
Fast execution: 12-month median trial duration is well below industry typical (~18–24mo).
Sources: DOL OFLC LCA Disclosure Data (public), ClinicalTrials.gov-derived sponsor analytics powered by TheraRadar, live job listings from this site.
Salary Ranges by Level
H1B-disclosed wages →Vertex Pharmaceuticals postings on CompBioJobs list a median posted salary of $155K-$232K across 38 roles that disclose annual pay (median posted minimum to median posted maximum, USD). By level: senior $131K-$197K; principal $164K-$247K; director $193K-$290K.
Senior
Principal
Director
Median posted minimum to median posted maximum across Vertex Pharmaceuticals postings on CompBioJobs (open and closed) that disclose annual base pay in USD. Levels with fewer than 6 such postings are not shown. Base salary only; excludes bonus and equity.
Interview Process
Disclaimer: Interview processes are approximate and may vary by role, level, team, and time. This information is based on public reports and may be outdated.
Interview processes change frequently — always verify with current candidates or recruiters.
Recruiter Screen
Hiring Manager Call
Technical Panel
Presentation (senior roles)
Final Round
📚 Verify & Prepare
Get detailed interview experiences from people who actually interviewed:
💡 Interview Tips
- • Practice data structures and algorithms on LeetCode/HackerRank
- • Study system design concepts for senior roles
- • Research Vertex Pharmaceuticals's products and tech stack
- • Prepare behavioral questions using the STAR method
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