Bioinformatics Jobs in California 2026
The largest biotech market in the US — Bay Area, San Diego, and beyond
California is the largest biotech and bioinformatics market in the United States, anchored by two major hubs: the San Francisco Bay Area (Genentech, 23andMe, 10x Genomics, Insitro, Nimbus, Recursion) and San Diego (Illumina, GRAIL, Tempus, Pacific Biosciences). The state hosts the highest concentration of computational biology PhDs, NIH research dollars, and venture capital in the country. Salaries are typically the highest in the industry to offset the cost of living, with senior bioinformatics roles commonly ranging from $180K to $300K+.
San Francisco
South San Francisco
San Diego
La Jolla
Berkeley
Emeryville
Palo Alto
Santa Clara
Pleasanton
200+ open positions
Research Engineer, Life Sciences
Anthropic · San Francisco, CA
· $350K-$500K
Scientist, Bioinformatics
Arc Institute · Palo Alto, CA
· $135K-$187K
Postdoctoral Researcher, ML for Biology, Hsu Lab
Arc Institute · Palo Alto, CA
Director, Machine Learning, Virtual Cell Initiative
Arc Institute · Palo Alto, CA
· $380K-$420K
Senior Principal Scientist I, Translational Disease Biology
Sanofi · Cambridge, MA
Director, Computational Biology
Arc Institute · Palo Alto, CA
· $234K-$288K
Machine Learning Research Lead, Alzheimer's Disease Initiative
Arc Institute · Palo Alto, CA
· $339K-$401K
Lead Bioinformatics Engineer
Quest Diagnostics · Secaucus, NJ
· $155K-$175K
Principal AI Lead – Surgical AI
Johnson & Johnson · Santa Clara, California, United States of America
· $157K-$271K
Senior Scientist, Systems Biology
Sanofi · Cambridge, MA
Senior Principal Scientist I, Lab Head, Protein Engineering
Sanofi · Cambridge, MA
Head, AI Delivery & Enablement (AIDE), Director
Pfizer · United States - Massachusetts - Cambridge
· $177K-$294K
Applied AI Workflow Scientist, Sr. Manager
Pfizer · United States - Massachusetts - Cambridge
· $139K-$232K
Statistician
Dana-Farber Cancer Institute · Boston Job Posting Location
· $82K-$99K
Director, Biostatistical Programming
Bristol-Myers Squibb · San Diego - RayzeBio - CA
· $227K-$276K
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)
Genentech · South San Francisco
· $148K-$274K
Senior Statistician, Early Development
Genentech · South San Francisco
· $137K-$254K
Principal Scientist (Computational Chemistry)
Genentech · South San Francisco
· $145K-$269K
Scientist, Pharmacokinetics
Merck (MSD) · USA - California - South San Francisco (Grand Ave)
· $108K-$170K
Senior Principal Scientist I - Functional Biomarkers
Sanofi · Cambridge, MA
Manager, Biostatistics
Pfizer · Cambridge, Massachusetts
· $106K-$177K
Data Scientist
New Flyer · Winnipeg, Winnipeg, Manitoba, Canada
· $80K-$95K
Senior Bioinformatics Engineer II
Moderna, Inc. · Cambridge, Massachusetts
Sr Data Scientist- Operations Research
Johnson & Johnson · Titusville, New Jersey, United States of America
· $109K-$175K
Senior Data Scientist - Business Innovation
Johnson & Johnson · Titusville, New Jersey, United States of America
· $109K-$175K
Data Scientist and Application Developer
Johnson & Johnson · Titusville, New Jersey, United States of America
· $98K-$158K
Senior Expert Data Science, Scientific Innovation
Novartis · Cambridge (USA)
· $139K-$257K
Senior Expert Data Science (Applied AI, LMW Drug Discovery)
Novartis · Cambridge (USA)
· $139K-$257K
Senior Scientist, Analytical Genomics
Novartis · Cambridge (USA)
· $94K-$174K
Senior Director, Data Science Solutions
Genentech · South San Francisco
Senior Principal Statistician, Early Development (Senior Director Level)
Genentech · South San Francisco
· $172K-$319K
Senior Scientist - Nucleic Acids Payload Engineering
Genentech · San Diego
· $108K-$201K
Principal Scientist, Lab Head, Integrative Neuroscience
Sanofi · Cambridge, MA
Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease Genomics
Sanofi · Cambridge, MA
· $149K-$215K
Data Engineer – Computational Biology (Senior Associate)
Pfizer · United States - Massachusetts - Cambridge
· $83K-$138K
Principal ML Scientist, Multimodal Biological Reasoning
Flagshippioneeringinc · Cambridge, MA USA
· $216K-$297K
Scientist / Senior Scientist, Multimodal AI
Altoslabs · San Francisco Bay Area, CA;San Diego, CA
· $201K-$258K
Scientific Fellow, AI-Enabled CMC
Sanofi · Cambridge (U.S.)
Principal Scientist, Imaging Analytics
Johnson & Johnson · New Brunswick, New Jersey, United States of America
· $117K-$201K
Sr Machine Learning Scientist
Amgen · Thousand Oaks, California
Scientist II, Bioinformatics QC
Aspen Neuroscience · San Diego, California
Head of Computational and AI Strategy Management Office, R&D
Sanofi · Cambridge, MA
· $179K-$258K
Associate Principal Scientist, Pharma R&D
Tempus AI · Boston, MA / New York, NY / Chicago, IL
· $155K-$210K
Lead, Search & Evaluation, AI and Automation Drug Discovery
Takeda · Cambridge, MA
· $177K-$278K
Associate Director, AI Enablement & Machine Learning
Flagshippioneeringinc · Cambridge, MA USA
· $212K-$318K
Senior Scientist II/Principal Scientist, Sequencing Technologies
Flagshippioneeringinc · Cambridge, MA USA
Scientist, Molecular Discovery
Merck (MSD) · USA - California - San Diego (Science Park Road)
· $87K-$137K
Data Scientist
MORSE Corp · Cambridge, Massachusetts
· $90K-$210K
Senior Data Scientist – Neuroscience Spatial Multi-omics
Merck (MSD) · USA - Massachusetts - Cambridge (320 Bent Street)
· $145K-$228K
Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)
Novartis · Cambridge (USA)
· $120K-$222K
Showing top 50 of 200 open positions. Browse all