ML Scientist I / II, Foundation Models for Life Sciences

Lila Sciences
Location
San Francisco, CA
Job Type
Full-time
Posted
May 22, 2026
Views
53
Salary Range
$176k - $304k USD

Job Description

Your Impact at Lila

Lila is building a platform where AI and automation co-evolve to solve the hardest problems in medicine. Within Life Science AI (LSAI), the Foundation Models team researches and develops large-scale generative models and reasoning frameworks that power automated scientific discovery across Lila's life science domains.

We are seeking a Scientist I or II to join this team as a contributor to foundation model research at the intersection of machine learning and life science data. You will work on generative models spanning biological sequences, molecular structures, and multimodal experimental data, contributing to problem formulation, model design, training, evaluation, and integration into Lila's closed-loop discovery engine.

This is an IC role for someone building deep expertise in generative AI applied to biology. You will own research sub-problems end to end, collaborate closely with experimental scientists to close the computational-experimental loop, and contribute to Lila's presence in the broader scientific community.

What You'll Be Building

Contribute to research on foundation models for life science applications, including biological sequence design, structure prediction, and multimodal scientific reasoning

Design, train, and evaluate generative models on biological and chemical data, incorporating domain-specific constraints and priors

Be part of the end-to-end ML process within Lila's "Lab-in-the-Loop" lifecycle: support data generation strategy, build pipeline models, and help design feedback loops where experimental results improve model performance

Translate biological questions into well-defined ML problems and interpret model outputs in collaboration with wet-lab scientists and computational biologists

Support research quality and methodology standards within the foundation models program

What You’ll Need to Succeed

PhD in Computer Science, Machine Learning, Computational Biology, or a related quantitative field (or Master's with equivalent research experience)

Strong foundation in generative model architectures and training, with hands-on experience in model development and evaluation

Ability to formulate and execute research independently, from problem definition through experimentation

Familiarity with at least one life science domain (molecular biology, genomics, protein engineering, nucleic acid design, or related)

Experience collaborating with experimental scientists or working with biological/chemical data

Proficiency in ML frameworks (PyTorch, JAX, or TensorFlow) and experience with GPU-based training workflows

Bonus Points For

Experience in computational protein design or molecular structure prediction

Experience with active learning loops or closed-loop experimental workflows

Contributions to open-source ML tools, frameworks, or benchmark datasets for scientific applications

Familiarity with distributed training infrastructure

High-impact publications or open‑source contributions in AI for Science in relevant venues (NeurIPS, ICML, ICLR, AAAAI, Nature Methods, Nature Biotechnology, or equivalent)

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range

$176,000—$304,000 USD

Your Impact at Lila

Lila is building a platform where AI and automation co-evolve to solve the hardest problems in medicine. Within Life Science AI (LSAI), the Foundation Models team researches and develops large-scale generative models and reasoning frameworks that power automated scientific discovery across Lila's life science domains.

We are seeking a Scientist I or II to join this team as a contributor to foundation model research at the intersection of machine learning and life science data. You will work on generative models spanning biological sequences, molecular structures, and multimodal experimental data, contributing to problem formulation, model design, training, evaluation, and integration into Lila's closed-loop discovery engine.

This is an IC role for someone building deep expertise in generative AI applied to biology. You will own research sub-problems end to end, collaborate closely with experimental scientists to close the computational-experimental loop, and contribute to Lila's presence in the broader scientific community.

What You'll Be Building

Contribute to research on foundation models for life science applications, including biological sequence design, structure prediction, and multimodal scientific reasoning

Design, train, and evaluate generative models on biological and chemical data, incorporating domain-specific constraints and priors

Be part of the end-to-end ML process within Lila's "Lab-in-the-Loop" lifecycle: support data generation strategy, build pipeline models, and help design feedback loops where experimental results improve model performance

Translate biological questions into well-defined ML problems and interpret model outputs in collaboration with wet-lab scientists and computational biologists

Support research quality and methodology standards within the foundation models program

What You’ll Need to Succeed

PhD in Computer Science, Machine Learning, Computational Biology, or a related quantitative field (or Master's with equivalent research experience)

Strong foundation in generative model architectures and training, with hands-on experience in model development and evaluation

Ability to formulate and execute research independently, from problem definition through experimentation

Familiarity with at least one life science domain (molecular biology, genomics, protein engineering, nucleic acid design, or related)

Experience collaborating with experimental scientists or working with biological/chemical data

Proficiency in ML frameworks (PyTorch, JAX, or TensorFlow) and experience with GPU-based training workflows

Bonus Points For

Experience in computational protein design or molecular structure prediction

Experience with active learning loops or closed-loop experimental workflows

Contributions to open-source ML tools, frameworks, or benchmark datasets for scientific applications

Familiarity with distributed training infrastructure

High-impact publications or open‑source contributions in AI for Science in relevant venues (NeurIPS, ICML, ICLR, AAAAI, Nature Methods, Nature Biotechnology, or equivalent)

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range

$176,000—$304,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

Frequently Asked Questions

Where is the job located?
This position is located in San Francisco, CA.
What is the expected salary range?
The expected base salary range is $176,000 to $304,000 USD. The final offer will depend on your background, expertise, and expected impact. The role includes bonus potential and early-stage equity.
What are the key responsibilities for this role?
You will contribute to foundation model research for life science applications, design, train, and evaluate generative models, and support the integration of models into Lila's closed-loop discovery engine, translating biological questions into well-defined ML problems.
What qualifications are required for this role?
A PhD in Computer Science, Machine Learning, Computational Biology, or a related field (or Master's with equivalent experience) is required. You'll also need a strong foundation in generative models and experience with ML frameworks like PyTorch, JAX, or TensorFlow.
What benefits are offered to US employees?
Full-time U.S. employees receive medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

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Job Information

Source: manual
AI Relevance: 92/100 (Highly relevant)
Remote Type: onsite
Experience: Mid
Allowed Locations: Worldwide
Skills & Tags:
AI machine learning generative AI foundation models protein design protein engineering computational biology genomics

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