Senior Clinical Data Manager

Revolution Medicines seeks a Senior Clinical Data Manager to oversee all aspects of data management for clinical trials of RAS-targeted oncology therapies, from documentation development through database lock.

Key Responsibilities

• Represent data management in study team meetings and provide updates
• Manage data management timelines and study deliverables coordination
• Generate and review study documents including Data Management Plans and Case Report Forms
• Provide oversight of database setup, migrations, and User Acceptance Testing
• Lead development of internal Data Review Plans and coordinate cross-functional reviews
• Perform data listing reviews and generate/resolve EDC queries
• Execute external data reconciliation and serious adverse event reconciliation
• Provide oversight of CRO/service providers and manage their progress
• Train internal and external team members on EDC systems
• Identify potential study issues and recommend solutions
• Support statisticians in clinical trial report production

Required Qualifications

• Bachelor's degree in health sciences, life sciences, mathematics, computer science, or health-related field
• Minimum 5 years of data management experience in pharmaceutical or biotechnology industry
• Solid knowledge of clinical data management principles and regulatory requirements
• Understanding of ICH, FDA, and GCP regulations and guidelines
• Strong technical skills with EDC systems, MS Office applications
• Knowledge of industry standards (CDISC, SDTM, CDASH)
• Experience with web-based Electronic Data Capture systems and thesauri like MedDRA
• Excellent verbal, written, and interpersonal skills

Preferred Qualifications

• CRO/Service provider management experience
• Prior oncology and solid tumor clinical trial experience
• Working knowledge of SAS

Compensation: $138,000 - $172,000 USD. Work arrangement: Hybrid (Redwood City, CA headquarters).