Sr. Scientist, AI/ML Biologics

Takeda's AI/ML organization is building a team to transform how medicines are discovered using AI and ML across the entire drug discovery process. We are seeking an innovative AI/ML scientist with a passion for leveraging AI/ML in antibody discovery and design to join our Large Molecule AI/ML team. Req: R0179222.

This role will be an embedded member of multidisciplinary project teams, integrating advanced computational methods with cutting-edge experimental strategies to advance biologics programs from discovery through candidate nomination and toward clinical development.

Key Responsibilities

• Develop and implement state-of-the-art AI/ML methodologies for antibody design and discovery
• Build and deploy ML algorithms for multi-parameter optimization of biologics (antibodies, antigens, ADCs)
• Build tools to incorporate data from Design-Predict-Make-Confirm cycles with automated experimental platforms
• Develop predictive models for protein design and developability engineering using large-scale NGS and proprietary data
• Manage and process large-scale biological datasets for model training and evaluation
• Apply NLP, ML, and generative AI to enhance therapeutic discovery
• Collaborate with biology, protein engineering, and data generation teams to drive programs toward IND

Qualifications

• PhD in a scientific discipline with 2+ years relevant experience (or MS with 8+ years, or BS with 10+ years)
• Proven track record developing ML models for chemical and biological data
• Experience with AI/ML-enabled molecular design, structural biology, or protein engineering
• Strong programming skills in Python; familiarity with deep learning frameworks

Base Salary: $137,000 – $215,270. Boston, MA.