Senior Manager, Oncology Data and AI Systems

Johnson & Johnson Innovative Medicine is recruiting for a Senior Manager, Oncology Data and AI Systems to join our Data, Data Science and Artificial Intelligence team (DDSAI). This position will be located on site at one of our offices in either Spring House PA, Cambridge MA, Titusville NJ, Raritan NJ, or San Diego CA (no fully remote option available).

The Senior Manager, Oncology Data and AI Systems will focus on building data and AI systems in Oncology R&D and support projects from across the business including Clinical, Pre-Clinical, Real World Data (RWD) and 'omics platforms.

Key Responsibilities

• Serve as both a people leader and a hands-on contributor accountable for the end-to-end design, development, and operation of scalable, AI-enabled data products supporting Oncology R&D.
• Drive integration of diverse data sources (e.g., biomarker labs, real-world data, pre-clinical and translational systems) into high-quality, reusable, AI-ready assets.
• Partner closely with Oncology R&D and Data Science stakeholders to shape, prioritize, and deliver against business-critical use cases. Translate complex scientific and operational needs into robust data products and AI systems that accelerate decision-making, improve study execution, and enhance probability of success.
• Collaborate with domain experts, such as Ontology, Knowledge graph, and Data Product Engineers to design and deliver future-proof, AI-ready data systems aligned with Oncology Strategy. Ensure solutions enable discoverability, reuse, and advanced analytics/GenAI applications.
• Implement standard enterprise-level data models and create new data models as needed.
• Leverage cloud-based technology platforms to accomplish data and AI goals.
• Lead the design and optimization of data pipelines and AI workflows for structured and unstructured data using technologies such as Python, SQL, AWS services and other relevant tools. Mentor and on-board new team members.
• Implement quality and performance standards and measure Key Performance Indicators (KPIs) to determine accuracy and consistency.
• Lead team in the development of Agile practices and agentic AI coding tools.
• Act as a thought leader across Data Science, Engineering, and Oncology domains, ensuring alignment with broader data product strategy and avoiding duplication through reuse and standardization.

Required Qualifications

• Advanced degree (Master's or equivalent) in Computer Science, Engineering, Life Sciences, or other relevant field is strongly preferred. (Bachelor's Degree with experience equivalency may be considered).
• 6+ years of experience in data engineering, including data modeling and database design, preferably in the healthcare industry.
• Proficiency in agentic AI coding tools, e.g. Claude Code, Codex, etc.
• Proficiency in data engineering tools such as Python and SQL for data processing as well as cloud architecture (e.g. AWS services, Redshift, FSx, Glue, Lambda).
• Experience with unstructured database technologies (e.g. NoSQL) as well as other database types (e.g. Graph).
• Strong skills in analysis, problem-solving, organizational change, project delivery, and managing external vendors. Proven record leading improvement initiatives with multi-disciplinary and remote partners. Demonstrated stakeholder management capabilities — including requirements gathering, business analysis and planning.
• Ability to manage numerous projects simultaneously, prioritize work, exhibit organizational skills and flexibility to deliver maximum business value.
• Willingness to conduct periodic travel (<15% of time) to conferences and internal meetings.

Preferred Qualifications

• Experience building Model Context Protocol (MCP) servers.
• Exposure to high dimensional data technologies and handling, including genomics and imaging.
• Familiarity with machine learning operations (MLOps) and model deployment.
• Experience with healthcare data standards (e.g. CDISC, HL7, FHIR, SNOMED CT, OMOP, DICOM).

The anticipated base pay range for this position is $137,000 to $235,750, plus an annual performance bonus and Company-sponsored benefits (medical, dental, vision, 401(k), pension, and paid time off). This position is located on site (hybrid) at one of Spring House PA, Cambridge MA, Titusville NJ, Raritan NJ, or San Diego CA — no fully remote option available.

Requisition number: R-083757. Job category: Senior Manager, Data Science (PL8). Function: Data Analytics & Computational Sciences / Data Science.