Director of Bioinformatics

Do you want to lead bioinformatics at a fast-paced, energizing molecular diagnostics company with an interdisciplinary team of scientists, programmers, and product builders? Are you ready to take cutting-edge digital PCR and NGS solutions for wastewater epidemiology, infectious disease surveillance, environmental testing, and cancer diagnostics from research-grade into clinical-grade production? If so, read on!

Located next to the foothills in beautiful Fort Collins, Colorado, GT Molecular is at the inflection point where our science needs production-grade software and clinical-grade bioinformatics — and we’re hiring the leader who will build it.

The Role

As Director of Bioinformatics you will own all bioinformatics and software at GTM. You’ll lead a small, technically excellent team and you’ll be the bridge between our R&D scientists, our wet lab, our operations team, our sales organization, and the CLIA-grade clinical world we’re stepping into in 2026.

Some of the projects you’ll lead:

• Whole Virome sequencing — Take our analytical pipeline platform to production with benchmarking and synthetic-data tooling that standardizes how we evaluate every future tool.

• CLIA-grade clinical readiness — using our patented multiplex oncology panels

• Production-grade infrastructure — CI/CD, testing, monitoring, versioning

• AI/ML as a core capability — including our first production ML pilot

• NGS pipeline expansion — extend our NGS offerings to additional pathogens using our unique chemistry

• Cross-functional leadership — partner to R&D, operations, sales, and the C-suite

Requirements

• PhD or MS plus 10+ years of equivalent experience in a quantitative field (computational biology, bioinformatics, data science, biomedical engineering, or related)

• This is a hands-on role — you will continue to contribute technically while leading the team. You will need a proven track record leading bioinformatics and data science teams in biotech, pharma, or diagnostics, including team management and stakeholder engagement at the C-suite/Board level.

• Extensive expertise in algorithmic approaches for genomic data analysis including NGS (DNAseq, RNAseq, WGS/WES, scRNAseq, spatial transcriptomics), variant detection, and tools/databases such as Seurat, BAM/VCF, and AlphaFold

• Proven experience designing, training, and deploying ML or AI models to production — not just exploratory notebooks. Includes model selection, evaluation, validation, deployment, and ongoing performance monitoring. Strong preference for ML applied to genomic, biomedical, or scientific data.

• Advanced proficiency in Python and R, including ML frameworks (PyTorch, TensorFlow, scikit-learn) for bioinformatics applications, ETL/ELT workflows, and best practices for high-throughput data in regulated settings

• Strong experience with Linux/Unix, cloud infrastructure (AWS services such as S3, EC2, Lambda, Redshift), and big data tools (Apache Spark, Snowflake, Databricks)

• Solid grasp of statistical principles, machine learning methods (classification, regression, deep learning), and best practices for high-throughput data in regulated settings

• Demonstrated ability to build, scale, and maintain bioinformatics pipelines using workflow managers such as Snakemake or Nextflow

• Track record of translating early-stage research workflows into production-grade, maintainable systems

• Excellent communication skills for interdisciplinary collaboration, with a history of mentoring and leading projects to completion

Preferred Skills

• Experience in CAP/CLIA-certified or GCP/GCLP-regulated environments, including computer system validation and SOP development

• Software leadership: version control (Git/GitHub), CI/CD (Jenkins), containerization (Docker), and infrastructure as code (Terraform)

• Object-oriented programming in Python or similar, with experience building reusable code libraries and APIs

• Explainable AI (XAI) or model interpretability experience

• Hands-on familiarity with mainstream molecular biology processes — NGS library prep, automation systems (Hamilton, Agilent), PCR/qPCR, liquid biopsy

• UI/UX expertise for data visualization tools (Plotly, Tableau, Spotfire) and custom dashboards in Python Dash or R Shiny

• Familiarity with databases (SQL, NoSQL such as MongoDB/DynamoDB) and clinical data systems (LIMS, EDC)

• Publications, patents, or code samples in bioinformatics, genomics, or ML for biology

• Prior Director or senior-manager role at a small or mid-size company where you wore multiple hats

What We Offer

• Base salary range: $180,000–$220,000 annually, depending on experience and qualifications

• Annual performance bonus

• Meaningful Stock Appreciation Rights (SARs) participation in a growing company

• Comprehensive benefits including health, dental, vision, 401(k) with match

• High-impact role with direct CEO access during a key growth phase

• Collaborative culture in scenic Fort Collins—outdoor access, innovative biotech community

Location

This is a hybrid role based in Fort Collins, Colorado. Strong preference for time in our Fort Collins lab/office multiple days per week. Local candidates preferred; relocation support is available. Fully remote with regular Fort Collins visits will be considered for exceptional candidates.

Additional Details

• Individuals seeking employment are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation.

• Equal opportunity / affirmative action employer.

• This role offers an exciting and creative environment with an interdisciplinary team passionate about the positive impact of our work.

To Apply

Submit the following at careers@gtmolecular.com – Please include “Director of Bioinformatics” in the subject line.

• A letter of motivation describing which of the five 2026 priorities above resonates most and why.

• Resume or CV in PDF format, highlighting relevant leadership roles, publications, patents, and code samples

• If selected for interview, names and contact information for three professional references

Applications without a letter of motivation will not be considered.

Scientist II, Research & Development

GT Molecular is seeking a creative, hands-on Scientist II to join our Research & Development team.

We’re looking for a scientist who loves tinkering, prototyping, and learning new techniques. This role is ideal for someone who enjoys working across a variety of projects, tackling ambiguous problems, and developing practical solutions where no established playbook exists.

The successful candidate will support a broad portfolio of R&D activities spanning molecular biology, genomics, assay development, and product development. They will independently design and execute experiments, develop and optimize new methods, and generate data that drive technical and product decisions.

Responsibilities

• Design, execute, analyze, and troubleshoot complex experiments in molecular biology and genomics, where no starting protocols may exist.

• Develop, optimize, and validate assays, workflows, and laboratory methods for NGS, dPCR, qPCR, and nucleic acid extraction

• Apply Design of Experiments (DOE) principles to efficiently optimize assays and workflows.

• Develop orthogonal assays and validation strategies to rapidly evaluate performance and guide development decisions.

• Analyze and communicate experimental results, recommendations, and next steps.

• Contribute to intellectual property, technical documentation, and product development activities.

• Collaborate with cross-functional teams to advance R&D and product development goals.

• Mentor and provide technical guidance to junior team members.

Qualifications

• PhD with 2-4 years, Master’s with 4-6 years, or Bachelor’s with 6-8 years of relevant experience.

• Strong hands-on experience in common molecular biology techniques

• Experience with NGS workflows, their enzymes, and library preparation is a must-have

• Experience using DOE and statistical approaches to guide experimental design

• Demonstrated ability to develop, optimize, and troubleshoot assays and experimental workflows.

• Strong data analysis, communication, and problem-solving skills.

The Ideal Candidate

• Loves figuring things out and trying new things

• Is comfortable with ambiguity and evolving priorities.

• Can move quickly between different technical challenges.

• Balances creativity with scientific rigor.

• Takes ownership and drives projects forward independently.

What We Offer

• Base salary range: $70,000-90,000 annually, depending on experience and qualifications

• Annual performance bonus

• Comprehensive benefits including health, dental, vision, 401(k) with match

• Collaborative culture in scenic Fort Collins—outdoor access, innovative biotech community

Location

This is an on-site role based in Fort Collins, Colorado.

Additional Details

• Individuals seeking employment are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation.

• Equal opportunity / affirmative action employer.

• This role offers an exciting and creative environment with an interdisciplinary team passionate about the positive impact of our work.

To Apply

Submit the following at careers@gtmolecular.com and include “Scientist II” in the subject line.

• A letter of motivation – Tell us, briefly: A problem you solved where no protocol existed, your hands-on NGS and library-prep experience, why GT Molecular, and why an on-site role in Fort Collins.

• Resume or CV in PDF format.

• If selected for interview, names and contact information for three professional references.

• Applications without a letter of motivation will not be considered