Lead Data Engineer

Flagship Pioneering
Location
Cambridge, MA USA
Job Type
Full-time
Posted
September 5, 2026
Views
5

Job Description

Who We Are

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

About Scientific Cloud: Scientific Cloud is Flagship Pioneering's portfolio-facing IT organization, responsible for the cloud engineering, data and informatics engineering, research systems, lab systems, and vendor management capabilities that power Flagship's emerging companies. The team operates with a portfolio-first orientation — building durable, shared infrastructure that individual ventures can rely on at every stage of company formation and growth.

We are seeking a Lead Data Engineer to lead complex initiatives aimed at modernizing and professionalizing our data infrastructure, platforms, and pipelines. You will lead the implementation of core platform systems and help to set the directions and standards of our data infrastructure and pipelines. You will work closely with other engineers and stakeholders across Infrastructure & Operations (I&O), Lab IT, Pioneering Intelligence (PI) Tech, and the internal scientific community to turn evolving scientific needs into secure, reliable and scalable data engineering solutions.

Reporting into the Associate Director, Data Architecture & Engineering, this is a technical, senior individual-contributor role that will champion engineering best practices, build complex data pipelines, lead data platform implementations, and handle the troubleshooting and optimization of data warehouse and storage solutions.

CORE RESPONSIBILITIES

Data & Platform Engineering

    Serve as the technical lead and subject matter expert on complex data engineering projects involving interdependent systems, legacy environments, and emerging cloud-first platforms.
    Lead the implementation of data infrastructure, platforms, tools, and other data products.
    Lead the optimization and reliability of data storage solutions (lakehouses, marts, warehouses, etc.).
    Implement complex backend and data integration pipelines to support data lakes, marts, and other platforms.
    Establish and reinforce engineering standards for testing, documentation, release management, and monitoring across the team.
    Lead implementations for platform observability, management, resilience, capacity, and performance.
    Diagnose and resolve complex failures spanning infrastructure and data pipelines; lead incident reviews and ensure corrective actions improve the wider system.

Cross-Functional Collaboration & Technical Leadership

    Collaborate across I&O, Lab IT, PI Tech, data science, and bioinformatics teams to ensure architectural alignment, reuse of components, and shared understanding of system states and dependencies.
    Mentor junior engineers and establish engineering standards that drive excellence, reproducibility, and innovation across the team.
    Leverage generative AI tools and frameworks to accelerate pipeline development, data transformation, and metadata enrichment at scale.

Who We Are

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

About Scientific Cloud: Scientific Cloud is Flagship Pioneering's portfolio-facing IT organization, responsible for the cloud engineering, data and informatics engineering, research systems, lab systems, and vendor management capabilities that power Flagship's emerging companies. The team operates with a portfolio-first orientation — building durable, shared infrastructure that individual ventures can rely on at every stage of company formation and growth.

We are seeking a Lead Data Engineer to lead complex initiatives aimed at modernizing and professionalizing our data infrastructure, platforms, and pipelines. You will lead the implementation of core platform systems and help to set the directions and standards of our data infrastructure and pipelines. You will work closely with other engineers and stakeholders across Infrastructure & Operations (I&O), Lab IT, Pioneering Intelligence (PI) Tech, and the internal scientific community to turn evolving scientific needs into secure, reliable and scalable data engineering solutions.

Reporting into the Associate Director, Data Architecture & Engineering, this is a technical, senior individual-contributor role that will champion engineering best practices, build complex data pipelines, lead data platform implementations, and handle the troubleshooting and optimization of data warehouse and storage solutions.

CORE RESPONSIBILITIES

Data & Platform Engineering

    Serve as the technical lead and subject matter expert on complex data engineering projects involving interdependent systems, legacy environments, and emerging cloud-first platforms.
    Lead the implementation of data infrastructure, platforms, tools, and other data products.
    Lead the optimization and reliability of data storage solutions (lakehouses, marts, warehouses, etc.).
    Implement complex backend and data integration pipelines to support data lakes, marts, and other platforms.
    Establish and reinforce engineering standards for testing, documentation, release management, and monitoring across the team.
    Lead implementations for platform observability, management, resilience, capacity, and performance.
    Diagnose and resolve complex failures spanning infrastructure and data pipelines; lead incident reviews and ensure corrective actions improve the wider system.

Cross-Functional Collaboration & Technical Leadership

    Collaborate across I&O, Lab IT, PI Tech, data science, and bioinformatics teams to ensure architectural alignment, reuse of components, and shared understanding of system states and dependencies.
    Mentor junior engineers and establish engineering standards that drive excellence, reproducibility, and innovation across the team.
    Leverage generative AI tools and frameworks to accelerate pipeline development, data transformation, and metadata enrichment at scale.

REQUIRED QUALIFICATIONS

    6+ years of hands-on experience in data engineering, preferably in life sciences, biotech, or healthcare environments...

Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The position is located in Cambridge, MA, USA. The job posting does not specify whether the work-mode policy is remote, hybrid, or on-site.
What are the key responsibilities of this role?
You will serve as technical lead on complex data engineering projects, implement data infrastructure and pipelines, optimize data storage solutions, establish engineering standards, and diagnose complex system failures. You will also collaborate cross-functionally with infrastructure, Lab IT, and scientific teams.
Who will I report to in this position?
In this senior individual-contributor role, you will report directly to the Associate Director, Data Architecture & Engineering.

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Job Information

Source: greenhouse
AI Relevance: 65/100 (Relevant)
Remote Type: onsite
Allowed Locations: Cambridge, MA USA
Skills & Tags:
IT

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