Structural Biologist III

Tempus AI
Tempus AI logo
Location
Ambry Headquarters
Job Type
Full-time
Posted
September 12, 2026
Views
5
Salary Range
$120k - $170k USD

Job Description

Compensation

$120,000 - $170,000

Role Overview

The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.

Key Responsibilities

  • Provide structural biology support for variant analyses through structure-function relationship interpretation.
  • Develop novel methods, protocols, and tools for structural modeling, molecular dynamics, and clinical variant assessment on internal platforms.
  • Partner with statisticians and data scientists to validate algorithms and data collection workflows.
  • Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical research projects.
  • Write testable, production-grade code adhering to SDLC standards and code review best practices.
  • Maintain technical documentation, SOPs, and knowledge bases while mentoring junior staff.
  • Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion
  • Support, inform, and educate leadership and stakeholders about project progress and blockers.

Qualifications & Competencies

  • Education: PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.
  • Experience: Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years of post-doctoral or industrial experience and 2 years management experience.
  • Technical Skills: Fluency/proficiency in scripting/languages (Python, R, Perl, C/C++, Java, SQL) and bioinformatics/modeling software. Strong background in systems biology, molecular dynamics, and experimental techniques (X-ray, Cryo-EM).

PRIVACY NOTICES

To review Ambry’s Privacy Notice, Click here:  https://www.ambrygen.com/legal/privacy-policy

To review the California privacy notice, click here: California Privacy Notice | Ambry Genetics

To review the UKG privacy notice, click here: California Privacy Notice | UKG

Equal Opportunity Employer

This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.

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Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The job is located at Ambry Headquarters. The posting does not specify a remote, hybrid, or on-site work-mode policy.
What are the key responsibilities of the Structural Biologist III?
You will support variant analyses, develop structural modeling and molecular dynamics tools, partner with data scientists to validate algorithms, write production-grade code, maintain technical documentation, and lead the structural team while mentoring junior staff.
What qualifications and experience are required for this role?
You need a PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent. Additionally, a minimum of 5 years of R&D experience in computational structural biology is required, including at least 2 years of post-doctoral or industrial experience and 2 years of management experience.
What technical skills are required?
You must be fluent or proficient in scripting and programming languages such as Python, R, Perl, C/C++, Java, and SQL, as well as bioinformatics and modeling software. A strong background in systems biology, molecular dynamics, and experimental techniques like X-ray and Cryo-EM is also required.
What is the salary range for this position?
The compensation range for this role is $120,000 - $170,000.

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Job Information

Source: manual
AI Relevance: 88/100 (Highly relevant)
Remote Type: onsite
Allowed Locations: Worldwide
Skills & Tags:
tempus ai bioinformatics computational biology structural biology clinical

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