Director, Multiomics Bioinformatics

Illumina
Location
US - California - San Diego
Job Type
Full-time
Posted
September 18, 2026
Views
50
Salary Range
$205k - $308k USD

Job Description

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

The Director, Bioinformatics will provide strategic leadership for Illumina's multiomics bioinformatics portfolio, spanning single cell, spatial biology, proteomics, epigenomics, and emerging multiomics technologies. Leading a team of bioinformatics scientists and engineers, this leader will define and execute informatics strategies that enable end-to-end customer multiomics workflows. The role will involve partnering closely with Product Management, Assay Development, Software Engineering, Clinical Development, and Commercial organizations to align bioinformatics capabilities with product roadmaps, customer needs, and business objectives.

Responsibilities:

  • Strategy -- define and drive bioinformatics strategy across Illumina's multiomics portfolio, including single cell, spatial biology, proteomics, epigenomics, and emerging multiomics technologies

  • Vision -- establish the long-term vision for customer-facing informatics experiences and end-to-end product workflows

  • Innovation -- drive innovation in analysis methods, AI-enabled workflows, and next-generation multiomics capabilities

  • Leadership -- lead, develop, and grow a team of bioinformatics scientists and engineers, and lead programs from concept through commercial launch

  • Partnership -- represent Bioinformatics and partner cross-functionally to develop technology roadmaps and investment priorities

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Requirements:

  • PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Genomics, or related scientific discipline, with 10+ years of relevant experience preferred

  • Demonstrated leadership experience managing complex bioinformatics organizations and programs

  • Track record of delivering customer-facing software, analytical methods, or informatics products, including support of commercial launches

  • Experience leading cross-functional product development initiatives

  • Strong understanding of NGS, genomics, transcriptomics, proteomics, or related multiomics technologies

  • Experience with cloud-scale informatics platforms, AI/ML technologies, and large-scale biological data analysis

  • Excellent communication and stakeholder management skills

All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.

Experience/ Education:

  • Typically requires a Bachelor’s degree and a minimum of 18 years of related experience, with 10+ years of Management experience.

#LI-ONSITE

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

The Director, Bioinformatics will provide strategic leadership for Illumina's multiomics bioinformatics portfolio, spanning single cell, spatial biology, proteomics, epigenomics, and emerging multiomics technologies. Leading a team of bioinformatics scientists and engineers, this leader will define and execute informatics strategies that enable end-to-end customer multiomics workflows. The role will involve partnering closely with Product Management, Assay Development, Software Engineering, Clinical Development, and Commercial organizations to align bioinformatics capabilities with product roadmaps, customer needs, and business objectives.

Responsibilities:

  • Strategy -- define and drive bioinformatics strategy across Illumina's multiomics portfolio, including single cell, spatial biology, proteomics, epigenomics, and emerging multiomics technologies

  • Vision -- establish the long-term vision for customer-facing informatics experiences and end-to-end product workflows

  • Innovation -- drive innovation in analysis methods, AI-enabled workflows, and next-generation multiomics capabilities

  • Leadership -- lead, develop, and grow a team of bioinformatics scientists and engineers, and lead programs from concept through commercial launch

  • Partnership -- represent Bioinformatics and partner cross-functionally to develop technology roadmaps and investment priorities

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Requirements:

  • PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Genomics, or related scientific discipline, with 10+ years of relevant experience preferred

  • Demonstrated leadership experience managing complex bioinformatics organizations and programs

  • Track record of delivering customer-facing software, analytical methods, or informatics products, including support of commercial launches

  • Experience leading cross-functional product development initiatives

  • Strong understanding of NGS, genomics, transcriptomics, proteomics, or related multiomics technologies

  • Experience with cloud-scale informatics platforms, AI/ML technologies, and large-scale biological data analysis

  • Excellent communication and stakeholder management skills

All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.

Experience/ Education:

  • Typically requires a Bachelor’s degree and a minimum of 18 years of related experience, with 10+ years of Management experience.

#LI-ONSITE

The estimated base salary range for the Director, Multiomics Bioinformatics role based in the United States of America is: $205,100 - $307,700. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Researching Illumina before you apply?

See 11 open roles · Verified H-1B salary data · Culture, benefits & locations.

View Illumina profile

Frequently Asked Questions

Where is the job located, and is it remote/hybrid/on-site?
The position is located in San Diego, California, and is an on-site role (#LI-ONSITE).
What are the required qualifications and experience levels for this role?
You should have a PhD in Bioinformatics or a related discipline with 10+ years of relevant experience preferred, or a Bachelor's degree with at least 18 years of related experience (including 10+ years of management experience). You also need experience managing complex bioinformatics organizations and delivering customer-facing informatics products.
What are the key responsibilities of the Director, Multiomics Bioinformatics?
You will define and drive the bioinformatics strategy and long-term vision for Illumina's multiomics portfolio. You will lead and grow a team of bioinformatics scientists and engineers, drive innovation in analysis methods and AI workflows, and partner cross-functionally to develop technology roadmaps.
What is the salary range for this position?
The estimated base salary range for this US-based role is $205,100 - $307,700. Most candidates are hired between the minimum and middle of this range.
Does this position offer visa sponsorship?
No, this role is not eligible for visa sponsorship.
What benefits and compensation packages are offered?
In addition to base salary, employees are eligible for variable cash programs (bonus/commission) and potentially equity. Benefits include access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

Ready to Apply?

Apply for this Position

You'll be redirected to the company's application page

Share this job:

Explore Illumina

Research the company before you apply.

  • 11 open roles
  • Verified H-1B salary data
  • Culture, benefits & locations
View company profile

Job Information

Source: workday
AI Relevance: 98/100 (Highly relevant)
Remote Type: onsite
Allowed Locations: US - California - San Diego
Skills & Tags:
illumina pharma

Get Similar Jobs by Email

Weekly digest of Illumina and similar companies. Free.

Related Jobs

Apply for this Position

Get weekly job alerts