Senior Principal Data Scientist

Johnson & Johnson
Johnson & Johnson logo
Location
Bangalore, Karnataka, India
Job Type
Full-time
Posted
October 22, 2026

Job Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Data Analytics & Computational Sciences

Job Sub Function

Data Science

Job Category

Scientific/Technology

All Job Posting Locations

Bangalore, Karnataka, India, Beerse, Antwerp, Belgium, Madrid - Lafinca, PENJERLA, Telangana, India

J&J Innovative Medicine – Data, Data Science, and AI - Global Development (DDSAI GD) is seeking a Senior Principal Data Scientist to set strategy and scale reusable analytical products across Global Development. This role leads cross-functional programs, platforms, governance, and adoption for ML, GenAI, optimization, and RWD capabilities that strengthen clinical operations, feasibility, patient access, quality, and portfolio performance.

Key Responsibilities

  • Set strategy and lead cross-functional programs that scale reusable ML, GenAI, optimization, and RWD products, platforms, and governance across Global Development.
  • Direct the design, deployment, and lifecycle management of reusable analytical platforms and products spanning clinical operations, feasibility, patient access, quality, and portfolio efficiency.
  • Define and scale RWD analytics capabilities using EHR, claims, registries, and clinical-trial data to generate decision-grade evidence for study and program design, patient populations, feasibility, and operational strategy.
  • Establish standards for solution architecture, validation, monitoring, governance, risk management, data quality, privacy, and responsible AI deployment.
  • Partner with senior leaders to prioritize high-value opportunities, shape roadmaps, manage strategic trade-offs, and drive scaled adoption across functions and therapeutic areas.
  • Measure and improve portfolio impact through product reuse, user adoption, cross-functional value, and performance against agreed outcomes.
  • Build organizational capability through reusable frameworks, productized solutions, shared practices, and mentorship of technical talent.
  • Serve as a senior technical advisor across clinical, operational, technology, and data functions.

Required Qualifications

  • Master’s degree in computer science, engineering, biostatistics, health economics, biomedical informatics, applied mathematics, or another quantitative discipline; PhD preferred.
  • At least 8 years of industry experience leading cross-functional programs and reusable data-science, AI, optimization, GenAI, or RWD capabilities.
  • Demonstrated experience setting technical direction and driving strategy, product scaling, governance, and adoption from opportunity identification through measurable impact.
  • Expertise in predictive modeling, optimization, simulation, GenAI, and RWD analytics in clinical development, clinical operations, healthcare, or a comparably complex regulated environment.
  • Experience overseeing production-ready analytical products or platforms with clear validation, performance-monitoring, and lifecycle-management standards.
  • Strong knowledge of model governance, MLOps, privacy, data quality, risk management, and responsible AI.
  • Proven executive influence and experience developing technical talent and cross-functional capability.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Data Analytics & Computational Sciences

Job Sub Function

Data Science

Job Category

Scientific/Technology

All Job Posting Locations

Bangalore, Karnataka, India, Beerse, Antwerp, Belgium, Madrid - Lafinca, PENJERLA, Telangana, India

J&J Innovative Medicine – Data, Data Science, and AI - Global Development (DDSAI GD) is seeking a Senior Principal Data Scientist to set strategy and scale reusable analytical products across Global Development. This role leads cross-functional programs, platforms, governance, and adoption for ML, GenAI, optimization, and RWD capabilities that strengthen clinical operations, feasibility, patient access, quality, and portfolio performance.

Key Responsibilities

  • Set strategy and lead cross-functional programs that scale reusable ML, GenAI, optimization, and RWD products, platforms, and governance across Global Development.
  • Direct the design, deployment, and lifecycle management of reusable analytical platforms and products spanning clinical operations, feasibility, patient access, quality, and portfolio efficiency.
  • Define and scale RWD analytics capabilities using EHR, claims, registries, and clinical-trial data to generate decision-grade evidence for study and program design, patient populations, feasibility, and operational strategy.
  • Establish standards for solution architecture, validation, monitoring, governance, risk management, data quality, privacy, and responsible AI deployment.
  • Partner with senior leaders to prioritize high-value opportunities, shape roadmaps, manage strategic trade-offs, and drive scaled adoption across functions and therapeutic areas.
  • Measure and improve portfolio impact through product reuse, user adoption, cross-functional value, and performance against agreed outcomes.
  • Build organizational capability through reusable frameworks, productized solutions, shared practices, and mentorship of technical talent.
  • Serve as a senior technical advisor across clinical, operational, technology, and data functions.

Required Qualifications

  • Master’s degree in computer science, engineering, biostatistics, health economics, biomedical informatics, applied mathematics, or another quantitative discipline; PhD preferred.
  • At least 8 years of industry experience leading cross-functional programs and reusable data-science, AI, optimization, GenAI, or RWD capabilities.
  • Demonstrated experience setting technical direction and driving strategy, product scaling, governance, and adoption from opportunity identification through measurable impact.
  • Expertise in predictive modeling, optimization, simulation, GenAI, and RWD analytics in clinical development, clinical operations, healthcare, or a comparably complex regulated environment.
  • Experience overseeing production-ready analytical products or platforms with clear validation, performance-monitoring, and lifecycle-management standards.
  • Strong knowledge of model governance, MLOps, privacy, data quality, risk management, and responsible AI.
  • Proven executive influence and experience developing technical talent and cross-functional capability.

Preferred Qualifications

  • Experience in pharmaceutical development, clinical research, clinical operations, real-world evidence, healthcare, or MedTech.
  • Experience establishing AI, analytics, or RWD strategy across multiple programs, therapeutic areas, or enterprise functions.
  • Experience leading analytics initiatives for feasibility, site and country selection, enrollment, patient access, protocol optimization, quality, or portfolio planning.

Required Skills

Preferred Skills

Advanced Analytics, Consulting, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Mentorship, Strategic Thinking, Tactical Planning, Technical Credibility

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Frequently Asked Questions

Where is the job located?
The primary job location is Bangalore, Karnataka, India. Additional listed locations include Penjerla, Telangana, India; Beerse, Antwerp, Belgium; and Madrid - Lafinca, Spain. The posting does not specify a remote, hybrid, or on-site work policy.
What qualifications and experience are required for this role?
Candidates need a Master’s degree in a quantitative discipline (PhD preferred) and at least 8 years of industry experience leading cross-functional programs and reusable data science, AI, GenAI, optimization, or RWD capabilities. Experience in predictive modeling, model governance, oversee production-ready platforms, and executive influence are also required.
What are the key responsibilities of the Senior Principal Data Scientist?
You will set strategy and lead programs to scale reusable ML, GenAI, optimization, and RWD products across Global Development. Responsibilities include directing platform lifecycles, defining RWD capabilities using EHR/claims data, establishing AI standards and governance, partnering with senior leaders, mentoring technical talent, and measuring portfolio impact.

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Job Information

Source: manual
AI Relevance: 80/100 (Highly relevant)
Remote Type: onsite
Skills & Tags:
johnson & johnson data science biostatistics clinical LLM

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