Bioinformatics Workflow Developer

Zifo
Location
Cary, North Carolina
Job Type
Full-time
Posted
October 24, 2026

Job Description

Design, develop, and productionize scalable bioinformatics workflows supporting pangenome graph construction, haplotype expansion, population-scale imputation, and genomic data quality control. This role focuses on transforming research-grade analyses into robust, reusable, and cloud-enabled pipelines that support large-scale multi-crop genomics programs.

Requirements

  • Develop and maintain production-grade bioinformatics workflows for pangenome, haplotype, imputation, and QC processes.
  • Convert research scripts and manual analyses into automated, version-controlled, and reproducible pipelines.
  • Work with genomic data formats including FASTA, GFF/GTF, VCF, BAM/CRAM, haplotype outputs, and associated metadata.
  • Implement workflows using cloud-native AWS services, leveraging S3 storage and scalable batch execution.
  • Build validation, logging, provenance tracking, and error-handling capabilities into workflows.
  • Collaborate with scientists and domain experts to ensure biological accuracy and usability of outputs.

Required Skills

  • Strong programming experience in Python, Nextflow, Snakemake, WDL, or similar workflow frameworks.
  • Experience processing large-scale genomics datasets and common bioinformatics file formats.
  • Familiarity with AWS cloud services and distributed computing environments.
  • Understanding of software engineering best practices, including Git, testing, CI/CD, and documentation.

Key Deliverables

  • Production-ready workflow modules and reusable pipeline templates.
  • Automated QC and validation reports.
  • Execution and operational documentation.
  • Reliable mechanisms for workflow monitoring, reprocessing, and onboarding of new datasets.

Benefits

About Zifo

CURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 7 of the Top 10 Biopharma companies.

We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals. While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability.

We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts.

If you share these sentiments and are prepared for the atypical, then Zifo is your calling!

Zifo is an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

CURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 18 of the Top 20 Biopharma companies.

We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals. While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability.

We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts.

Design, develop, and productionize scalable bioinformatics workflows supporting pangenome graph construction, haplotype expansion, population-scale imputation, and genomic data quality control. This role focuses on transforming research-grade analyses into robust, reusable, and cloud-enabled pipelines that support large-scale multi-crop genomics programs.

Requirements

  • Develop and maintain production-grade bioinformatics workflows for pangenome, haplotype, imputation, and QC processes.
  • Convert research scripts and manual analyses into automated, version-controlled, and reproducible pipelines.
  • Work with genomic data formats including FASTA, GFF/GTF, VCF, BAM/CRAM, haplotype outputs, and associated metadata.
  • Implement workflows using cloud-native AWS services, leveraging S3 storage and scalable batch execution.
  • Build validation, logging, provenance tracking, and error-handling capabilities into workflows.
  • Collaborate with scientists and domain experts to ensure biological accuracy and usability of outputs.

Required Skills

  • Strong programming experience in Python, Nextflow, Snakemake, WDL, or similar workflow frameworks.
  • Experience processing large-scale genomics datasets and common bioinformatics file formats.
  • Familiarity with AWS cloud services and distributed computing environments.
  • Understanding of software engineering best practices, including Git, testing, CI/CD, and documentation.

Key Deliverables

  • Production-ready workflow modules and reusable pipeline templates.
  • Automated QC and validation reports.
  • Execution and operational documentation.
  • Reliable mechanisms for workflow monitoring, reprocessing, and onboarding of new datasets.

Benefits

About Zifo

CURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 7 of the Top 10 Biopharma companies.

We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals. While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability.

We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts.

If you share these sentiments and are prepared for the atypical, then Zifo is your calling!

Zifo is an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

CURIOSITY DRIVEN, SCIENCE FOCUSED, EMPLOYEE BUILT. Our culture is unlike any other, one where we debate, challenge ourselves, and interact with all alike. We are a curious bunch, characterized by our passion to learn and spirit of teamwork. Zifo is a global R&D solutions provider focused on the industries of Pharma, Biotech, Manufacturing QC, Medical Devices, specialty chemicals and other research-based organizations. Our team’s knowledge of science and expertise in technology help Zifo better serve our customers around the globe, including 18 of the Top 20 Biopharma companies.

We look for Science – Biotechnology, Pharmaceutical Technology, Biomedical Engineering, Microbiology etc. We possess scientific and technical knowledge and bear professional and personal goals. While we have a “no doors” policy to promote free access within, we do have a tough door to walk in. We search with a two-point agenda – technical competency and cultural adaptability.

We offer a competitive compensation package including accrued vacation, medical, dental, vision, 401k with company matching, life insurance, and flexible spending accounts.

If you share these sentiments and are prepared for the atypical, then Zifo is your calling!

Zifo is an equal opportunity employer, and we value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Frequently Asked Questions

Where is this job located, and is remote work available?
The position is located in Cary, North Carolina. The job posting does not specify a remote, hybrid, or on-site work-mode policy.
What are the key responsibilities of this role?
You will design, develop, and maintain production-grade, cloud-enabled bioinformatics workflows for pangenome construction, haplotype expansion, imputation, and QC processes. Tasks include converting research scripts into automated, reproducible pipelines, working with common genomic data formats, using AWS services, implementing logging and validation, and collaborating with scientists to ensure biological accuracy.
What qualifications and skills are required?
Candidates need strong programming experience in Python and workflow frameworks like Nextflow, Snakemake, or WDL. Requirements also include experience processing large-scale genomics datasets, familiarity with AWS cloud services and distributed computing, and an understanding of software engineering best practices such as Git, testing, CI/CD, and documentation.
What benefits does Zifo offer?
Zifo offers a competitive compensation package that includes accrued vacation, medical, dental, and vision insurance, a 401(k) with company matching, life insurance, and flexible spending accounts.

Ready to Apply?

Apply for this Position

You'll be redirected to the company's application page

Share this job:
WhatsApp LinkedIn X Email

Job Information

Source: manual
AI Relevance: 95/100 (Highly relevant)
Remote Type: onsite
Skills & Tags:
zifo bioinformatics genomics
Explore related roles:

Get Similar Jobs by Email

Weekly digest of Zifo and similar companies. Free.

Related Jobs

Apply for this Position

Get weekly job alerts