Postdoctoral Research Fellow - Optical Imaging in Neuroimaging

Mass General Brigham
Location
Charlestown-MA
Job Type
Full-time
Posted
November 4, 2026
Salary Range
$72k - $74k USD

Job Description

Site: Massachusetts General Physicians Organization, Inc.

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

APPLY BY EMAIL ONLY - APPLICATION INSTRUCTIONS BELOW

The proposed project involves advancing polarization sensitive optical coherence tomography (PSOCT) to reveal the 3D neuronal architecture and connectivity in the developmental cerebellum. The overarching goal is to map the cerebellum development in the first years and to understand the impact of prematurity (preterm infants) in cerebellum growth and the overall development. We are seeking a highly motivated candidate with an interest in biomedical optics and neuroimaging. The candidate will be working directly with Drs Hui Wang and Lilla Zollei, integrated into the Hui Wang Lab, part of Laboratories for Computational Neuroimaging (https://lcn.martinos.org/) at the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School. This project involves a highly collaborative environment and interaction with multidisciplinary teams. The Fellow will obtain training in independent research and grant writing and will have great opportunities to launch an independent investigation.

The Wang lab develops novel optical imaging tools that combines with MRI, molecular labeling, and computational modeling to study the underlying structures supporting the complex functions in the brain. One focus area is to develop next generation large-scale microscopic imaging techniques to map the neuroarchitecture, vasculature, and connectivity in the whole brain and study alternations in neurological disorders.

Responsibilities

  • Optical system design, test, and characterization.
  • Volumetric microscopy data processing, physical model based data analysis, and data interpretation.
  • Experimental design; work with research technicians to conduct data collection and analysis.
  • Present progresses to our collaborators and in scientific conferences; publish the work in a timely manner; support future grant applications.
  • Collaborate with other research members and clinical staff to further advance the goals of the research project

Qualifications

Qualification requirements

  • Ph.D. in optics, biomedical engineering, electrical engineering, physics, or a related field.
  • Strong research background in biomedical optics, microscopy, or optical engineering.
  • Ability to work independently and with additional training to become an independent researcher.
  • Excellent written and verbal communication skills, demonstrated by publication and conference presentation records.
  • Experience with optical design, simulation, 3D CAD design, and programing language in control, DAQ, and real time data processing is desired.
  • Research experience with polarization sensitive optical coherence tomography is a strong plus.
  • Strong computational skills, such as signal processing, optimization, or machine learning is a plus.
  • Research experience in neuroimaging is preferred, but not required.

The appointment is for two years with the possibility of continuation based on annual performance evaluation.

The salary range for this position is $71,750 to $73,544 annually.

Additional Job Details (if applicable)

IMPORTANT – APPLICATION INSTRUCTIONS

Please do not apply through the Workday “Apply” button.

This position is being posted for informational purposes only. To be considered, please submit the following directly to the hiring manager by clicking the link below:

  • CV/resume
  • Cover letter describing research interests and experience
  • Contact information for three references

📧 hwang47@mgh.harvard.edu

Site: Massachusetts General Physicians Organization, Inc.

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

APPLY BY EMAIL ONLY - APPLICATION INSTRUCTIONS BELOW

The proposed project involves advancing polarization sensitive optical coherence tomography (PSOCT) to reveal the 3D neuronal architecture and connectivity in the developmental cerebellum. The overarching goal is to map the cerebellum development in the first years and to understand the impact of prematurity (preterm infants) in cerebellum growth and the overall development. We are seeking a highly motivated candidate with an interest in biomedical optics and neuroimaging. The candidate will be working directly with Drs Hui Wang and Lilla Zollei, integrated into the Hui Wang Lab, part of Laboratories for Computational Neuroimaging (https://lcn.martinos.org/) at the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School. This project involves a highly collaborative environment and interaction with multidisciplinary teams. The Fellow will obtain training in independent research and grant writing and will have great opportunities to launch an independent investigation.

The Wang lab develops novel optical imaging tools that combines with MRI, molecular labeling, and computational modeling to study the underlying structures supporting the complex functions in the brain. One focus area is to develop next generation large-scale microscopic imaging techniques to map the neuroarchitecture, vasculature, and connectivity in the whole brain and study alternations in neurological disorders.

Responsibilities

  • Optical system design, test, and characterization.
  • Volumetric microscopy data processing, physical model based data analysis, and data interpretation.
  • Experimental design; work with research technicians to conduct data collection and analysis.
  • Present progresses to our collaborators and in scientific conferences; publish the work in a timely manner; support future grant applications.
  • Collaborate with other research members and clinical staff to further advance the goals of the research project

Qualifications

Qualification requirements

  • Ph.D. in optics, biomedical engineering, electrical engineering, physics, or a related field.
  • Strong research background in biomedical optics, microscopy, or optical engineering.
  • Ability to work independently and with additional training to become an independent researcher.
  • Excellent written and verbal communication skills, demonstrated by publication and conference presentation records.
  • Experience with optical design, simulation, 3D CAD design, and programing language in control, DAQ, and real time data processing is desired.
  • Research experience with polarization sensitive optical coherence tomography is a strong plus.
  • Strong computational skills, such as signal processing, optimization, or machine learning is a plus.
  • Research experience in neuroimaging is preferred, but not required.

The appointment is for two years with the possibility of continuation based on annual performance evaluation.

The salary range for this position is $71,750 to $73,544 annually.

Additional Job Details (if applicable)

IMPORTANT – APPLICATION INSTRUCTIONS

Please do not apply through the Workday “Apply” button.

This position is being posted for informational purposes only. To be considered, please submit the following directly to the hiring manager by clicking the link below:

  • CV/resume
  • Cover letter describing research interests and experience
  • Contact information for three references

📧 hwang47@mgh.harvard.edu

Please note: Applications submitted through Workday will not be forwarded to the hiring manager and may not be reviewed.

Remote Type

Onsite

Work Location

149 Thirteenth Street Building 149

EEO Statement

1300 Massachusetts General Physicians Organization, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Frequently Asked Questions

Where is this job located, and what is the work setting?
The position is located in Charlestown, MA (149 Thirteenth Street, Building 149). It is an fully onsite role.
What qualifications are required for this position?
Applicants must hold a Ph.D. in optics, biomedical engineering, electrical engineering, physics, or a related field. Requirements include a strong background in biomedical optics, microscopy, or optical engineering, independent work capability, and excellent written and verbal communication skills demonstrated through publications and conference presentations.
What are the key responsibilities of this role?
Responsibilities include optical system design, testing, and characterization; volumetric microscopy data processing and analysis; designing experiments and collaborating on data collection; presenting progress to collaborators and conferences; publishing timely work; supporting grant applications; and collaborating with research and clinical staff.
What is the salary range for this position?
The salary range for this position is $71,750 to $73,544 annually.
How do I apply for this position and what materials are required?
Do not apply through Workday. Candidates must apply by emailing their CV/resume, a cover letter describing research interests and experience, and contact information for three references directly to hwang47@mgh.harvard.edu.
Who will I report to and work with?
You will work directly with Drs. Hui Wang and Lilla Zollei within the Hui Wang Lab, part of the Laboratories for Computational Neuroimaging at the Athinoula A. Martinos Center for Biomedical Imaging (Massachusetts General Hospital/Harvard Medical School), alongside multidisciplinary research teams.

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Remote Type: onsite
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