Senior Manager, Biostatistics (Late Stage) (m/f/d)

Position leads complex studies in study design, statistical analysis and interpretation of results with some supervision. This position contributes to specific aspects of drug development plans with minimal supervision and contributes to documents submitted to Health Authorities globally with some supervision. This position also guides contract research organization (CRO) programmers and statisticians in preparing analysis files and performing statistical analyses. Additionally, this position interacts with study teams, as well as statisticians and programmers at CROs. This position works under some supervision to solve complex study problems. The primary location for this position is France, with Germany as the secondary location.

Responsibilities

• Protocol Development, Case Report Form (CRF; review), Statistical Analysis Plan (SAP), Statistical Analysis, Results Interpretation, and clinical study report (CSR).

• Leads statistical activities for complex studies, including study design, protocol development, CRF review, SAP development, analysis file development, statistical analysis accuracy validation, results interpretation, and CSR input and review.

• Acts as the main statistical contact for the assigned studies and projects.

• Provides guidance to the study team on all aspects of statistical activities; collaborates closely with the data manager to ensure high-quality data.

• Drug Development Strategy: Provides input to multiple aspects of the development plan to ensure the study designs at each phase of development are scientifically sound, can fulfill regulatory requirements, and deliver the pre-specified product profile.

• CRO / Vendor Oversight: Reviews CRO/vendor proposals and budgets. Establishes procedures through regular interaction, setting expectations for deliverables and timelines to guide CRO biostatisticians and statistical programmers on complex studies.

• Ensures deliverables are accurate and delivered according to the timelines.

• Global Health Authority Interaction / Negotiation: Contributes to documents submitted to Health Authorities globally by providing input for the interaction or by writing the interaction document. May participate in meetings or teleconferences with Health Authorities.

• Global BDO Strategy to Improve Drug Development: Primarily participates in and may occasionally lead moderately complex initiatives, with some level of supervision, to improve the harmonization and efficiency of drug development, which leads to cost savings and shortened timelines for the company.

Qualifications

Education Qualifications

• Master’s degree in statistics or biostatistics required.

• PhD in statistics or biostatistics preferred.

Experience Qualifications

• 8+ years of relevant experience in the pharmaceutical industry with a master’s degree required.

• 5+ years of relevant experience in the pharmaceutical industry with a PhD preferred.

Travel Requirements

Ability to travel up to 10% of the time.