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Protein Design Jobs

Protein design jobs use computational methods, including structure prediction, protein language models, and generative diffusion models, to design novel binders, enzymes, and antibodies and to predict how they fold and function. It is one of the fastest-growing corners of AI in biotech, concentrated in protein-design startups, platform biotechs, and pharma discovery teams. Browse open roles below, from scientist to principal, with compensation for experienced scientists and engineers frequently reaching $200K and beyond.

24 new this week 34 with salary 2 remote
Amgen
Fresh

Senior Scientist - Computational Protein Design

Amgen

South San Francisco, California 5d ago
X
Fresh AI: 95

AI in Residence, Computational Protein Design

Xairatherapeutics

Seattle, Washington, United States $10-15k 5d ago
S
Fresh AI: 92

Scientist-Principal Scientist, Protein Design & Structure

Superluminal Medicines

Boston, MA 5d ago
G
Fresh AI: 95

Scientist I / Scientist II, Computational Protein Design

Generate Biomedicines

Somerville, MA 6d ago
Moderna
Recent

Principal Scientist, Computational Protein Design

Moderna

Cambridge, Massachusetts 7d ago
L
Recent AI: 95

Computational Protein Designer

Latent Labs

London 7d ago
M
AI: 95

Sr. Scientist, Generative Protein Design

Merck (MSD)

USA - Massachusetts - Cambridge (320 Bent Street) $131-207k 3w ago
X
AI: 96

AI Scientist, Computational Protein Design

Xaira Therapeutics

South San Francisco, California, United States $120-240k Jun 27
P
AI: 92

Scientist II, ML - Guided Protein Design Evaluation

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site) Jun 24
M
AI: 95

Senior Specialist, Computational Protein Design

Merck (MSD)

USA - California - South San Francisco (Grand Ave) $145-228k Jun 18
A
AI: 92

Senior Scientist - Computational Protein Design/Bioinformatics

Abcam

Cambridge, United Kingdom May 30
Bristol Myers Squibb
AI: 92

Principal Scientist, Computational Sciences - Protein Structure Prediction and Design

Bristol Myers Squibb

San Diego, CA $157-190k May 30
A
Fresh AI: 65

Forward Deployed Scientist

Adaptyv Bio

Lausanne / Hybrid / Remote 5d ago
A
Fresh AI: 88

Data Scientist, Lab & Protein Data

Adaptyv Bio

Lausanne 5d ago
G
Fresh AI: 92

Research Scientist, Applied Science

GenBio AI

Palo Alto, CA $200-270k 5d ago
G
Fresh AI: 93

Senior Machine Learning Scientist I/II, Model-Driven Optimization

Generate Biomedicines

Somerville, MA $192-265k 6d ago
C
Fresh AI: 92

Research Scientist

Chai Discovery

San Francisco office 6d ago
C
Fresh AI: 88

Antibody Engineering

Chai Discovery

San Francisco office 6d ago
C
Fresh AI: 95

Research Engineer

Chai Discovery

San Francisco office 6d ago
Gilead
Fresh AI: 92

Senior Scientist, AI/ML (Biologics Design)

Gilead

United States - California - Foster City $169-219k 6d ago
L
Recent AI: 90

Machine Learning Scientist

Latent Labs

London 7d ago
L
Recent AI: 75

Forward Deployed AI Engineer

Latent Labs

London 7d ago
L
Recent AI: 88

Member of Technical Staff, Applied AI

Latent Labs

London 7d ago
L
Recent AI: 90

Member of Technical Staff

Latent Labs

London 7d ago
D
Recent AI: 92

Sr. Machine Learning Engineer - Machine Learning

Dyno Therapeutics

Remote; Watertown, Massachusetts, United States $179-214k 7d ago
X
Recent AI: 75

Software Engineer, X-Scientist

Xaira Therapeutics

South San Francisco, California, United States $140-215k Jun 11
Flagship Pioneering
Recent AI: 85

Senior Scientist, Protein Engineering

Flagship Pioneering

Cambridge, MA USA $126-182k 1w ago
B
Recent AI: 95

Computational Biologist

Boltz

London, UK 1w ago
B
Recent AI: 92

Computational Antibody Engineer

Barrington James

Cambridgeshire, England 1w ago
AstraZeneca
Recent AI: 88

Scientist, Data Science

AstraZeneca

Waltham, Massachusetts $91-137k 1w ago
P
AI: 65

Senior Software Engineer, Data Platform

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site) May 11
Lila Sciences
AI: 92

Co-Op, ML Scientist for Protein Engineering

Lila Sciences

San Francisco, CA USA 2w ago
P
AI: 82

Software Engineer, Machine Learning Platform

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site) 2w ago
E
AI: 95

Research Scientist - Computational Biologist

Elanco

Indianapolis, IN 2w ago
Flagship Pioneering
AI: 92

Principal Scientist, Machine Learning

Flagship Pioneering

Cambridge, MA USA $208-286k 2w ago
P
AI: 65

Scientist II, mRNA Research & Production

Profluent

Emeryville, California, United States; On-site 3w ago
Genentech
AI: 95

Machine Learning Scientist, Structure-Function ML, AI for Drug Discovery (AIDD)

Genentech

New York $141-262k Jul 25
P
AI: 92

Machine Learning Research Engineer

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site) Jul 23
A
AI: 88

Research Scientist, Life Sciences (Computational)

Anthropic

San Francisco, CA $300-320k Jul 17
M
AI: 92

AI/ML Research Engineer

Manifold Bio

Boston, MA or San Francisco, CA $140-225k Jul 17
M
AI: 88

Computational Scientist, Assay Development

Manifold Bio

Boston $118-138k Jul 17
M
AI: 65

Senior Scientist, Biocatalysis

Merck (MSD)

USA - New Jersey - Rahway $117-184k Jul 17
S
AI: 92

Senior Scientist I, Data Science

Sail Biomedicines

Cambridge, MA Jul 14
S
AI: 95

Director, Computational & Protein Sciences

Stylus Medicine

Cambridge, Massachusetts, United States $245-265k Jul 14
X
AI: 65

Senior Scientist, Protein Engineering

Xaira Therapeutics

South San Francisco, California, United States $150-170k Jul 13
C
AI: 90

Machine Learning / Senior Machine Learning Scientist / Engineer

Calico

South San Francisco, CA $170-240k Jul 12
AstraZeneca
AI: 92

Associate Principal Scientist, Biologics AI

AstraZeneca

US - Cambridge Kendall SQ - MA $145-217k Jul 8
B
AI: 92

Research Scientist, AI

Biohub

New York, NY (Hybrid) $214-375k Jul 3
Sanofi
AI: 65

Senior Principal Scientist I, Lab Head, Protein Engineering

Sanofi

Cambridge, MA Jul 3
Flagship Pioneering
AI: 95

Principal ML Scientist, Multimodal Biological Reasoning

Flagship Pioneering

Cambridge, MA USA $216-297k Jun 30
Amgen
AI: 88

Sr Machine Learning Scientist

Amgen

Thousand Oaks, California Jun 30
M
AI: 75

Scientist, Molecular Discovery

Merck (MSD)

USA - California - San Diego (Science Park Road) $87-137k Jun 29
T
AI: 92

Senior Director, AIRx Biologics Discovery Lead

Takeda

Boston, Massachusetts $212-333k Jun 27
Pfizer
AI: 95

Senior Scientist, AI‑Enabled Structural Biology

Pfizer

United States - Connecticut - Groton $94-156k Jun 26
T
AI: 92

Sr. Scientist, AI/ML Biologics

Takeda

Boston, MA $137-215k Jun 18
Pfizer
AI: 92

AI/ML Engineer - Vaccines Modeling and Antigen Discovery

Pfizer

United States - New York - Pearl River $106-177k Jun 16
Pfizer
AI: 92

Postdoctoral Fellow, AI/ML Applications for Vaccine

Pfizer

United States - New York - Pearl River $65-108k Jun 14
P
AI: 95

Lead Bioinformatics Scientist, NGS

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site) Apr 24
AstraZeneca
AI: 65

Senior Scientist; Protein and Cell Sciences

AstraZeneca

UK - Cambridge Jun 10
Flagship Pioneering
AI: 95

Principal Scientist, Machine Learning - Biomolecules

Flagship Pioneering

Cambridge, MA USA Jun 10
G
AI: 95

Senior Scientist, Machine Learning (Biologics Design)

Gilead

United States - California - Foster City $169-219k Jun 9
P
AI: 95

Machine Learning Scientist, BioML

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site) Jun 5
G
AI: 65

Sr Scientist -- Biologics Engineering, Protein Therapeutics

Gilead

United States - California - Foster City $169-219k Jun 3
AstraZeneca
AI: 98

Executive Director, Head of Computational Discovery & Translation, Infectious Disease

AstraZeneca

US - Boston - MA Jun 3
P
AI: 92

Machine Learning Scientist, Reinforcement Learning

Profluent

Emeryville, California, United States; Hybrid (2-3 days on-site) Jun 3
P
AI: 85

Scientist II - Sr. Scientist, CRISPR Specificity & Genomic Safety

Profluent

Emeryville, California, United States; On-site Jun 2
Adaptive Biotechnologies
AI: 92

Principal Machine Learning Scientist

Adaptive Biotechnologies

Remote $183-275k Jun 2
Pfizer
AI: 85

Senior Scientist, Computational Biotherapeutics Engineering

Pfizer

United States - Massachusetts - Cambridge $94-156k May 29

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